N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide

Discontinued Product

0722 has been discontinued.

View all NO Donors / Precursors products.
说明: Nitroxyl precursor
说明书
引用文献
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生物活性

A pro-drug of the potent vasorelaxant nitroxyl, H-N=O, which it slowly releases in neutral solution. HNO eventually dimerizes and dehydrates to N2O, without producing NO. Also a powerful inhibitor of aldehyde dehydrogenase.

技术数据

分子量 291.71
公式 C10H10ClNO5S
储存 Desiccate at +4°C
CAS Number 142867-52-5
PubChem ID 688598
InChI Key GWYBSWWLKXEDLB-UHFFFAOYSA-N
Smiles ClC1=CC=C(S(N(C(C)=O)OC(C)=O)(=O)=O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献

参考文献是支持产品生物活性的出版物。

Fukuto et al (1992) N,O-Diacylated-N-hydroxyarylsulfonamides: nitroxyl precursors with potent smooth muscle relaxant properties. Biochem.Biophys.Res.Commun. 187 1367 PMID: 1417812

Lee et al (1992) Prodrugs of nitroxyl as inhibitors of aldehyde dehydrogenase. J.Med.Chem. 35 3648 PMID: 1433175

关键词: N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide, N-Acetyl-N-acetoxy-4-chlorobenzenesulfonamide supplier, Nitroxyl, precursor, ROS, Donors, NO, Precursors, Nitric, Oxide, Signaling, Signalling, /, 0722, Tocris Bioscience

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