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Submit ReviewNα-Methylhistamine dihydrochloride
Discontinued Product
0573 has been discontinued.
View all Histamine H<sub>3</sub> Receptors products.
说明： Non-selective H3 agonist
化学名： N-Methyl-1H-imidazole-4-ethanamine dihydrochloride
生物活性 for Nα-Methylhistamine dihydrochloride
Nα-Methylhistamine dihydrochloride is a potent histamine agonist, particularly at H3 receptors (potency relative to histamine is 81, 185, and 270% at H1, H2 and H3 respectively). Also displays agonist properties at H4 receptors to which it binds with moderate affinity (Ki = 23 nM).
技术数据 for Nα-Methylhistamine dihydrochloride
| 分子量 | 198.09 |
| 公式 | C6H11N3.2HCl |
| 储存 | Desiccate at RT |
| CAS Number | 16503-22-3 |
| PubChem ID | 16078977 |
| InChI Key | AYUQICXJAMPXPF-UHFFFAOYSA-N |
| Smiles | Cl.Cl.CNCCC1=CNC=N1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Nα-Methylhistamine dihydrochloride
参考文献 for Nα-Methylhistamine dihydrochloride
参考文献是支持产品生物活性的出版物。
Hill et al (1990) Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol.Rev. 42 45 PMID: 2164693
Schwartz et al (1990) A third histamine receptor subtype - characterization, localization and functions of the H3-receptor. Agents Actions 30 13 PMID: 1695431
Zweig et al (1992) Characterization of digitonin-solubilized bovine brain H3 histamine receptor coupled to a guanine nucleotide-binding protein. J.Neurochem. 59 1661 PMID: 1328529
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关键词: N-Methylhistamine dihydrochloride, N-Methylhistamine dihydrochloride supplier, Non-Selective, H3, agonists, Receptors, Histamine, histaminergic, Nalpha-Methylhistamine, dihydrochloride, 0573, Tocris Bioscience
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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Written by Iwan de Esch and Rob Leurs, this review provides a synopsis of the different histamine receptor subtypes and the ligands that act upon them; compounds available from Tocris are listed.
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