N¹,N¹²-Diethylspermine tetrahydrochloride

Name: N 1 , N 12 -Diethylspermine tetrahydrochloride
Brand: Tocris Bioscience
SKU: 0500

Cat. No. 0500 提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

0500 has been discontinued.

View all Other Synthases/Synthetases products.

说明： Polyamine synthase inhibitor

说明书

引用文献

生物活性技术数据说明书参考文献

生物活性

N¹,N¹²-Diethylspermine tetrahydrochloride is a powerful antineoplastic agent in cultured cells and animal tumors (IC₅₀ = 0.2 μM in L1210 cells). Inhibitor of polyamine synthases. Suppressor of mitochondrial DNA synthesis.

技术数据

分子量	404.29
公式	C₁₄H₃₄N₄.4HCl
储存	Store at RT
CAS Number	113812-15-0
PubChem ID	11750054
InChI Key	SCYOBNRPMHJGLB-UHFFFAOYSA-N
Smiles	CCNCCCNCCCCNCCCNCC.Cl.Cl.Cl.Cl

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书

分析证书/产品说明书

化学品安全技术说明书

参考文献

参考文献是支持产品生物活性的出版物。

Bergeron et al (1988) Synthetic polyamine analogues as antineoplastics. J.Med.Chem. 31 1183 PMID: 3373487

Bergeron et al (2005) Synthesis and bioloigcal evaluation of aminopolyamines. J.Med.Chem. 48 3099 PMID: 15857111

Porter et al (1990) Combined regulation of arginine and S-adenosylmethionine decarboxylases by spermine and the spermine analogue N¹,N¹²-bis(ethyl)spermine. Biochem.J. 268 207 PMID: 2344358

Vertino et al (1991) Selective cellular depletion of mitochondrial DNA by the polyamine analog N¹,N¹²-bis(ethyl)spermine and its relationship to polyamine structure and function. Mol.Pharmacol. 39 487 PMID: 2017149

按标靶查看相关产品

关键词: N1,N12-Diethylspermine tetrahydrochloride, N1,N12-Diethylspermine tetrahydrochloride supplier, Polyamine, synthase, inhibitors, inhibits, Synthases, Synthetases, Other, Synthases/Synthetases, 0500, Tocris Bioscience

篇 N¹,N¹²-Diethylspermine tetrahydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。

目前没有 N¹,N¹²-Diethylspermine tetrahydrochloride 的引用文献。