Naltrexone hydrochloride

Pricing Availability   Qty
说明: Non-selective opioid antagonist
化学名: (5α)-17-(Cyclopropylmethyl)-4,5-epoxy-3,14-dihydromorphinan-6-one hydrochloride
纯度: ≥99% (HPLC)
说明书
引用文献 (9)
评论
文献 (2)

生物活性 for Naltrexone hydrochloride

Naltrexone hydrochloride is an opioid antagonist.

技术数据 for Naltrexone hydrochloride

分子量 377.87
公式 C20H23NO4.HCl
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 16676-29-2
PubChem ID 11957643
InChI Key RHBRMCOKKKZVRY-ITLPAZOVSA-N
Smiles Cl.[H][C@@]12OC3=C(O)C=CC4=C3[C@@]11CCN(CC3CC3)[C@]([H])(C4)[C@]1(O)CCC2=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Naltrexone hydrochloride

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 37.79 100

制备储备液 for Naltrexone hydrochloride

以下数据基于产品分子量 377.87。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 2.65 mL 13.23 mL 26.46 mL
5 mM 0.53 mL 2.65 mL 5.29 mL
10 mM 0.26 mL 1.32 mL 2.65 mL
50 mM 0.05 mL 0.26 mL 0.53 mL

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产品说明书 for Naltrexone hydrochloride

分析证书/产品说明书
选择另一批次:

参考文献 for Naltrexone hydrochloride

参考文献是支持产品生物活性的出版物。

Gold et al (1982) Naltrexone, opiate addiction, and endorphins. Med.Res.Rev. 2 211 PMID: 6289026

Tempel et al (1982) Supersensitivity of brain opiate receptor subtypes after chronic naltr. treatment. Life Sci. 31 1401 PMID: 6292636

Zukin et al (1982) Naltrexone-induced opiate receptor supersensitivity. Brain Res. 245 285 PMID: 6289965


If you know of a relevant reference for Naltrexone hydrochloride, please let us know.

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查看全部 Miscellaneous Opioid Antagonists

关键词: Naltrexone hydrochloride, Naltrexone hydrochloride supplier, Broad, spectrum, antagonists, Opioids, Receptors, Miscellaneous/Non-selective, 0677, Tocris Bioscience

9 篇 Naltrexone hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Naltrexone hydrochloride 的部分引用包括:

Smith et al (2016) Endogenous central amygdala mu-opioid receptor signaling promotes sodium appetite in mice. Proc Natl Acad Sci U S A 113 13893 PMID: 27849613

Leskelä et al (2012) Cys-27 variant of human δ-opioid receptor modulates maturation and cell surface delivery of Phe-27 variant via heteromerization. J Biol Chem 287 5008 PMID: 22184124

Chung et al (2010) Hyperbaric oxygen treatment induces a 2-phase antinociceptive response of unusually long duration in mice. Hum Mol Genet 11 847 PMID: 20418186

Jones et al (2010) Identification of a κ-opioid agonist as a potent and selective lead for drug development against human African trypanosomiasis. Biochem Pharmacol 80 1478 PMID: 20696141


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该领域的文献

Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!

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