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Submit ReviewNCS-382
说明： Antagonist of γ-hydroxybutyric acid
化学名： 6,7,8,9-Tetrahydro-5-hydroxy-5H-benzocyclohept-6-ylideneacetic acid
纯度： ≥99% (HPLC)
生物活性 for NCS-382
NCS-382 is a γ-Hydroxybutyric acid antagonist, anticonvulsant.
技术数据 for NCS-382
| 分子量 | 218.25 |
| 公式 | C13H14O3 |
| 储存 | Desiccate at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 520505-01-5 |
| PubChem ID | 5875451 |
| InChI Key | UADPGHINQMWEAG-CSKARUKUSA-N |
| Smiles | OC1C2=C(CCC\C1=C/C(O)=O)C=CC=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for NCS-382
分析证书目前不在网上提供。
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参考文献 for NCS-382
参考文献是支持产品生物活性的出版物。
King et al (1997) Gammahydroxybutyrate (GHB) receptor ligand effects on evoked synaptic field potentials in CA1 of the rat hippocampal slice. J.Neural Transm. 104 1177 PMID: 9503264
Maitre et al (1990) A specific γ-hydroxybutyrate receptor ligand possesses both antagonist and anticonvulsant properties. J.Pharmacol.Exp.Ther. 255 657 PMID: 2173754
Schmidt et al (1991) Anti-sedative and anti-cataleptic properties of NCS-382, a γ-hydroxybutyrate receptor antagonist. Eur.J.Pharmacol. 203 393 PMID: 1773824
关键词: NCS-382, NCS-382 supplier, antagonists, γ-hydroxybutyric, gamma-hydroxybutyric, acid, GABAA, GABAC, Receptors, GABAB, anticonvulsant, Miscellaneous, GABA, 0780, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
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GABA Receptors Scientific Review
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.