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Submit ReviewNicergoline
Discontinued Product
0604 has been discontinued.
View all Non-selective Adrenergic α Receptors products.
说明： α antagonist
化学名： (8β)-10-methoxy-1,6-dimethylergoline-8-methanol 5-bromo-3-pyridine carboxylate ester
生物活性 for Nicergoline
Nicergoline is a α-adrenergic, vasodilator. Cognitive enhancer.
技术数据 for Nicergoline
| 分子量 | 484.39 |
| 公式 | C24H26BrN3O3 |
| 储存 | Store at RT |
| CAS Number | 27848-84-6 |
| PubChem ID | 90479736 |
| InChI Key | GCNGMFQQSBSPIJ-XPXYHQFPSA-N |
| Smiles | [H][C@](COC(C5=CN=CC(Br)=C5)=O)1C[C@@](C2=CC=CC3C2C(C4)=CN3C)(OC)[C@]4([H])N(C1)C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Nicergoline
参考文献 for Nicergoline
参考文献是支持产品生物活性的出版物。
Carfagna et al (1995) Modulation of hippocampal ACh release by chronic nicergoline treatment in freely moving young and aged rats. Neurosci.Lett. 197 195 PMID: 8552297
Carfagna et al (1996) Modulation of phosphoinositide turnover by chronic nicergoline in rat brain. Neurosci.Lett. 209 189 PMID: 8736642
Chopin and Briley (1992) Effects of four non-cholinergic cognitive enhancers in comparison with tac. and galanthamine on scopolamine-induced amnesia in rats. Psychopharmacology 106 26 PMID: 1738791
Merck Index 12 6580
关键词: Nicergoline, Nicergoline supplier, α-adrenoceptor, alpha-adrenoceptor, a-adrenoceptor, antagonists, α-adrenergic, alpha-adrenergic, a-adrenergic, Receptors, Non-Selective, vasodilator, Non-selective, Adrenergic, Alpha, 0604, Tocris Bioscience
1 篇 Nicergoline 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Nicergoline 的部分引用包括：
Woo et al (2007) Neuregulin-1 enhances depolarization-induced GABA release. Neuron 54 599 PMID: 17521572
Nicergoline 的评论
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.