Nisoxetine hydrochloride

Cat. No. 1025 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Noradrenalin re-uptake inhibitor

化学名： (±)-γ-(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride

纯度： ≥99% (HPLC)

引用文献 (5)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Nisoxetine hydrochloride

Nisoxetine hydrochloride is a potent and selective inhibitor of noradrenalin uptake with little or no affinity for a range of other neurotransmitter receptors.

技术数据 for Nisoxetine hydrochloride

分子量	307.82
公式	C₁₇H₂₁NO₂.HCl
储存	Store at RT
纯度	≥99% (HPLC)
CAS Number	57754-86-6
PubChem ID	134453
InChI Key	LCEURBZEQJZUPV-UHFFFAOYSA-N
Smiles	Cl.CNCCC(OC1=CC=CC=C1OC)C1=CC=CC=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Nisoxetine hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	30.78	100

制备储备液 for Nisoxetine hydrochloride

以下数据基于产品分子量 307.82。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.25 mL	16.24 mL	32.49 mL
5 mM	0.65 mL	3.25 mL	6.5 mL
10 mM	0.32 mL	1.62 mL	3.25 mL
50 mM	0.06 mL	0.32 mL	0.65 mL

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产品说明书 for Nisoxetine hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Nisoxetine hydrochloride

参考文献是支持产品生物活性的出版物。

Cheetham et al (1996) [³H]Nisoxetine - a radioligand for noradrenaline reuptake sites: correlation with inhibition of [³H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments. Neuropharmacology 35 63 PMID: 8684598

Shearman and Meyer (1998) NE transporters in rat placenta labeled with [³H]nisoxetine. J.Pharmacol.Exp.Ther. 284 736 PMID: 9454822

Wong et al (1975) dl-N-Methyl-3-(o-methoxyphenoxy)-3-phenylpropylamine hydrochloride, Lilly 94939, a potent inhibitor for uptake of NE into rat brain synaptosomes and heart. Life Sci. 17 755 PMID: 1207394

Zhu et al (1997) Down-regulation of NE transporters on PC12 cells by transporter inhibitors. J.Neurochem. 68 134 PMID: 8978719

If you know of a relevant reference for Nisoxetine hydrochloride, please let us know.

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