Nitrendipine

Discontinued Product

0601 has been discontinued.

View all Ca<sub>V</sub>1.x Channels (L-type) products.
说明: CaV1.x blocker
化学名: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine dicarboxylic acid ethyl methyl ester
纯度: ≥99% (HPLC)
说明书
引用文献 (3)
评论 (1)

生物活性 for Nitrendipine

Nitrendipine is a L-type calcium channel blocker. Induces autophagy.

技术数据 for Nitrendipine

分子量 360.37
公式 C18H20N2O6
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 39562-70-4
PubChem ID 4507
InChI Key PVHUJELLJLJGLN-UHFFFAOYSA-N
Smiles CCOC(=O)C1=C(C)NC(C)=C(C1C1=CC(=CC=C1)[N+]([O-])=O)C(=O)OC

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for Nitrendipine

参考文献是支持产品生物活性的出版物。

Costa et al (1996) Characterization of a voltage-dependent L-type calcium channel from rabbit and turtle brain. Neurochem.Res. 21 537 PMID: 8726959

Watanabe et al (1995) L-type calcium channel block by highly hydrophilic dihydropyridines in single ventricular cells of guinea-pig hearts. J.Mol.Cell.Cardiol. 27 1271 PMID: 8531209

Merck Index 12 6667

Fleming et al (2011) Chemical modulators of autophagy as biological probes and potential therapeutics. Nat.Chem.Biol. 7 9 PMID: 21164513

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关键词: Nitrendipine, Nitrendipine supplier, Ca2+, channel, blockers, L-type, Calcium, CaV, Channels, voltage-gated, voltage-dependent, Cav1.x, Autophagy, 0601, Tocris Bioscience

3 篇 Nitrendipine 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Nitrendipine 的部分引用包括:

Rosenkranz et al (2009) Regulation of protease-activated receptor-1 by vasodilatory prostaglandins via NFAT. Cardiovasc Res 83 778 PMID: 19460777

Schmitz et al (2009) Glutamate controls growth rate and branching of DArgic axons. J Neurosci 29 11973 PMID: 19776283

Subramanian and Morozov (2011) Erk1/2 inhibit synaptic vesicle exocytosis through L-type calcium channels. J Neurosci 31 4755 PMID: 21430174


Nitrendipine 的评论

平均评分: 5 (Based on 1 Review.)

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Nitrendipine was measured against other calcium channel blockers.
By Anonymous on 02/20/2019
种属: Human

Nitrendipine blocks L-type calcium channels in smooth muscle cells and its effectiveness was measured against other calcium channel blockers.

review image