Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewNocistatin (bovine)
说明： Opposes action of nociceptin
生物活性 for Nocistatin (bovine)
An endogenous peptide derived from the same precursor as nociceptin, which is able to block nociceptin-induced allodynia and hyperalgesia and may play an opposing role in pain transmission. Shown to reverse nociceptin inhibition of glutamate release from rat brain slices; also modulates 5-HT transmission in the mouse neocortex via mechanisms separate from nociceptin/orphanin FQ.
技术数据 for Nocistatin (bovine)
| 分子量 | 1927.07 |
| 公式 | C82H135N21O32 |
| 序列 | TEPGLEEVGEIEQKQLQ |
| 储存 | Desiccate at -20°C |
| CAS Number | 208253-85-4 |
| PubChem ID | 24868191 |
| InChI Key | GUPWDFZVRDNEEX-GFTPUIGSSA-N |
| Smiles | [H]N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Nocistatin (bovine)
参考文献 for Nocistatin (bovine)
参考文献是支持产品生物活性的出版物。
Fantin et al (2007) Nocistatin inhibits 5-hydroxytryptamine release in the mouse neocortex via presynaptic Gi/o protein linked pathways. Br.J.Pharmacol. 152 549 PMID: 17618307
Nicol et al (1998) Nocistatin reverses nociceptin inhibition of glutamate release from rat brain slices. Eur.J.Pharmacol. 356 R1 PMID: 9774260
Okuda-Ashitaka et al (1998) Nocistatin, a peptide that blocks nociceptin action in pain transmission. Nature 392 286 PMID: 9521323
Yamamoto et al (1999) Effect of nocistatin and its interaction with nociceptin/orphanin FQ on the rat formalin test. Neurosci.Lett. 262 179 PMID: 10218885
按产品操作查看相关产品
关键词: Nocistatin (bovine), Nocistatin (bovine) supplier, blocker, nociceptin, receptors, ORL1, OP4, NOP, opioid, reverses, Receptors, 1118, Tocris Bioscience
Nocistatin (bovine) 的评论
目前没有该产品的评论。 Be the first to review Nocistatin (bovine) and earn rewards!
Have you used Nocistatin (bovine)?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Peptides Involved in Appetite Modulation Scientific Review
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.