Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewNoradrenaline bitartrate
说明： Endogenous adrenergic hormone and neurotransmitter
别名： Norepinephrine
化学名： 4-[(1R)-2-Amino-1-hydroxyethyl]-1,2-benzenediol (L-(+))-bitartrate salt
纯度： ≥99% (HPLC)
生物活性 for Noradrenaline bitartrate
Noradrenaline bitartrate is an endogenous adrenergic hormone and neurotransmitter. A classical stress hormone; underlies the fight or flight response, along with adrenaline. Increases heart rate. Vasoconstrictor.
技术数据 for Noradrenaline bitartrate
| 分子量 | 319.26 |
| 公式 | C8H11NO3.C4H6O6 |
| 储存 | Store at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 51-40-1 |
| PubChem ID | 25127519 |
| InChI Key | WNPNNLQNNJQYFA-YIDNRZKSSA-N |
| Smiles | O[C@@H](CN)C1=CC(O)=C(O)C=C1.OC([C@H](O)[C@@H](O)C(O)=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for Noradrenaline bitartrate
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 31.93 | 100 | |
| DMSO | 31.93 | 100 |
制备储备液 for Noradrenaline bitartrate
以下数据基于产品分子量 319.26。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 3.13 mL | 15.66 mL | 31.32 mL |
| 5 mM | 0.63 mL | 3.13 mL | 6.26 mL |
| 10 mM | 0.31 mL | 1.57 mL | 3.13 mL |
| 50 mM | 0.06 mL | 0.31 mL | 0.63 mL |
Molarity Calculator
Molarity Calculator
Calculate the mass, volume, or concentration required for a solution.
Reconstitution Calculator
Reconstitution Calculator
Dilution Calculator
Dilution Calculator
Calculate the dilution required to prepare a stock solution.
产品说明书 for Noradrenaline bitartrate
参考文献 for Noradrenaline bitartrate
参考文献是支持产品生物活性的出版物。
Bunney et al (1965) NE in depressive reactions. A review. Arch.Gen.Psychiatry. 13 483 PMID: 5320621
Gary et al (1985) Stress and brain noradrenaline: A review. Neuroscience & Biobehavioral Reviews 9 233
Lewitt et al (2012) NE: the next therapeutics frontier for Parkinson's disease. Transl.Neurodegener. 1 4 PMID: 23211006
If you know of a relevant reference for Noradrenaline bitartrate, please let us know.
按标靶查看相关产品
关键词: Noradrenaline bitartrate, Noradrenaline bitartrate supplier, endogenous, adrenergic, hormones, neurotransmitters, vasoconstrictor, stress, 108341-18-0, Norepinephrine, Non-selective, Adrenergic, Alpha, Receptors, Beta, Transporters, 5169, Tocris Bioscience
9 篇 Noradrenaline bitartrate 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Noradrenaline bitartrate 的部分引用包括：
S et al (2023) Chronic intermittent ethanol exposure disrupts stress-related tripartite communication to impact affect-related behavioral selection in male rats. Neurobiol Stress 24 100539 PMID: 37131490
Asya et al (2021) Optogenetic activation of local colonic sympathetic innervations attenuates colitis by limiting immune cell extravasation. Immunity 54 1022-1036.e8 PMID: 33932356
Jordi et al (2022) Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice. J Neurochem 160 218-233 PMID: 34816436
Xinzhong et al (2022) Synchronized cluster firing, a distinct form of sensory neuron activation, drives spontaneous pain. Neuron 110 209-220.e6 PMID: 34752775
David E et al (2022) A serotonergic axon-cilium synapse drives nuclear signaling to alter chromatin accessibility. Cell 185 3390-3407.e18 PMID: 36055200
Thomas C et al (2019) Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell 179 498-513.e22 PMID: 31585084
Khaled et al (2020) Delta glutamate receptor conductance drives excitation of mouse dorsal raphe neurons. Elife 9 PMID: 32234214
Baj et al (2012) Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacology 37 1600 PMID: 22318196
Zemkova et al (2011) NE causes a biphasic change in mammalian pinealocye membrane potential: role of alpha1B-adrenoreceptors, phospholipase C, and Ca2+. Endocrinology 152 3842 PMID: 21828176
您是否知道使用了 Tocris Noradrenaline bitartrate 的优秀论文？ 请告知我们.
Noradrenaline bitartrate 的评论
平均评分: 4.7 (基于 3 条评论。)
Have you used Noradrenaline bitartrate?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by:
Noradrenaline is used in culture of HL-1 cells..
By
Anonymous on 07/05/2019
分析类型： In Vitro
种属： Mouse
细胞系/组织： HL-1
HL-1 cells were cultured in Claycomb medium with 10% FBS, 1 % penicillin/ streptomycin, 0.1 mM noradrenaline and 2 mM L-glutamine.
Noradrenaline elevates cardiomyocytes shortening.
By
Christopher Trummer on 10/22/2018
分析类型： In Vitro
种属： Mouse
细胞系/组织： Primary ventricular cardiomyocytes
Primary mouse ventricular cardiomyocytes were treated with Noradrenaline bitartrate (NA, 5 µM) for 5 min and stimulated at 1 Hz frequency to follow cell shortening. NA increased cell shortening (shown in Image).
Vasoconstrictor.
By
Anonymous on 10/02/2018
分析类型： Ex Vivo
种属： Mouse
Elicits vasoconstriction within minutes. Used at 10 uM
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.