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NPE-caged-proton

Cat. No. 3512 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Caged proton
别名： NPE-caged-sulfate
化学名： 1-(2-Nitrophenyl)ethyl sulfate sodium salt
纯度： ≥98% (HPLC)
说明书
引用文献
评论 (1)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for NPE-caged-proton

NPE-caged-proton is a 1-(2-nitrophenyl)ethyl caged proton that releases a proton and a sulfate ion upon photolysis at 350 - 355 nm. Generates rapid acidifications (pH jumps) down to pH 2.

技术数据 for NPE-caged-proton

分子量 269.21
公式 C8H8NNaO6S
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 1186195-63-0
PubChem ID 57369362
InChI Key LCCXAXUWDTVOHF-UHFFFAOYSA-M
Smiles [O-][N+](C1=C(C(C)OS([O-])(=O)=O)C=CC=C1)=O.[Na+]

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for NPE-caged-proton

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 26.92 100
DMSO 26.92 100

制备储备液 for NPE-caged-proton

以下数据基于产品分子量 269.21。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 3.71 mL 18.57 mL 37.15 mL
5 mM 0.74 mL 3.71 mL 7.43 mL
10 mM 0.37 mL 1.86 mL 3.71 mL
50 mM 0.07 mL 0.37 mL 0.74 mL

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产品说明书 for NPE-caged-proton

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for NPE-caged-proton

参考文献是支持产品生物活性的出版物。

Barth and Corrie (2002) Characterization of a new caged proton capable of inducing large pH jumps. Biophys.J. 83 2864 PMID: 12414718

Abbruzzetti et al (2005) Kinetics of proton release after flash photolysis of 1-(2-Nitrophenyl)ethyl sulfate (caged sulfate) in aqueous solution. J.Am.Chem.Soc. 127 9865 PMID: 15998092

Peralvarez-Marin et al (2008) Time-resolved infrared spectroscopy of pH-induced aggregation of the Alzheimer Aβ1-28 peptide. J.Mol.Biol. 379 589 PMID: 18462754

If you know of a relevant reference for NPE-caged-proton, please let us know.

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关键词: NPE-caged-proton, NPE-caged-proton supplier, Caged, proton, Compounds, NPEC-caged-sulfate, Other, 3512, Tocris Bioscience

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NPE Caged-proton.
By Anonymous on 07/17/2020
种属： Human

When photolyzed Caged-proton is supposed to reduce pH; even strong 365nm UV (~1W/cm^2) for 1 second did not show any change in pH

***Bio-Techne Response: Thank you for reviewing our product. We are sorry to hear that this antibody did not perform as expected. We have been in touch with the customer to resolve this issue according to our Product Guarantee and to the customer’s satisfaction. We suggested using a shorter wavelength for photolysis and offered a replacement vial, but we did not receive a response. ***