Octopamine hydrochloride

Discontinued Product

2242 has been discontinued.

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说明: Invertebrate biogenic amine: activates β3 adrenoceptors
别名: (±)-p-Octopamine,Epirenor,Norfen
化学名: α-(Aminomethyl)-4-hydroxybenzenemethanol hydrochloride
纯度: ≥99% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)

生物活性 for Octopamine hydrochloride

Invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β3 receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3 receptor activation but stimulates transport when oxidized by MAO. Also activates human α2A receptors, inhibiting subsequent cAMP production.

技术数据 for Octopamine hydrochloride

分子量 189.64
公式 C8H11NO2.HCl
储存 Desiccate at RT
纯度 ≥99% (HPLC)
CAS Number 770-05-8
PubChem ID 20592
InChI Key PUMZXCBVHLCWQG-UHFFFAOYSA-N
Smiles Cl.NCC(O)C1=CC=C(O)C=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

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产品说明书 for Octopamine hydrochloride

参考文献 for Octopamine hydrochloride

参考文献是支持产品生物活性的出版物。

Airriess et al (1997) Selective inhibition of adenylyl cyclase by octopamine via a human cloned α2A-adrenoceptor. Br.J.Pharmacol. 122 191 PMID: 9313925

Roeder (1999) Octopamine in invertebrates. Prog.Neurobiol. 59 533 PMID: 10515667

Visentin et al (2001) Dual action of octopamine on glucose transport into adipocytes: inhibition via β3-adrenoceptor activation and stimulation via oxidation by amine oxidases. J.Pharmacol.Exp.Ther. 299 96 PMID: 11561068

Carpene et al (1999) Selective activation of β3-adrenoceptors by octopamine: comparative studies in mammalian fat cells. Naunyn-Schmied.Arch.Pharmacol. 359 310

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1 篇 Octopamine hydrochloride 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Octopamine hydrochloride 的部分引用包括:

Li et al (2017) Pericytes impair capillary blood flow and motor function after chronic spinal cord injury. Nat Med 23 733 PMID: 28459438


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