OGT 2115

Cat. No. 2710 4 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Antiangiogenic. Heparanase inhibitor

化学名： 2-[4-[[3-(4-Bromophenyl)-1-oxo-2-propenyl]amino]-3-fluorophenyl]-5-benzoxazoleacetic acid

纯度： ≥97% (HPLC)

引用文献 (4)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for OGT 2115

OGT 2115 is a heparanase inhibitor (IC₅₀ = 0.4 μM) that displays no major inhibition of human cytochrome P450 isoenzymes (IC₅₀ > 30 μM). Exhibits antiangiogenic properties in vitro (IC₅₀ = 1 μM).

技术数据 for OGT 2115

分子量	495.3
公式	C₂₄H₁₆BrFN₂O₄
储存	Store at RT
纯度	≥97% (HPLC)
CAS Number	853929-59-6
PubChem ID	44402523
InChI Key	LKBXWNYXDMSFQU-ONNFQVAWSA-N
Smiles	O=C(/C=C/C4=CC=C(Br)C=C4)NC(C(F)=C3)=CC=C3C2=NC1=CC(CC(O)=O)=CC=C1O2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for OGT 2115

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	DMSO	4.95	10

制备储备液 for OGT 2115

以下数据基于产品分子量 495.3。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
0.1 mM	20.19 mL	100.95 mL	201.9 mL
0.5 mM	4.04 mL	20.19 mL	40.38 mL
1 mM	2.02 mL	10.09 mL	20.19 mL
5 mM	0.4 mL	2.02 mL	4.04 mL

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产品说明书 for OGT 2115

分析证书/产品说明书

化学品安全技术说明书

参考文献 for OGT 2115

参考文献是支持产品生物活性的出版物。

McKenzie (2007) Heparanase: a target for drug discovery in cancer and inflammation. Br.J.Pharmacol. 151 1 PMID: 17339837

Courtney et al (2005) Furanyl-1,3-thiazol-2-yl and benzoxazol-5-yl acetic acid derivates: novel classes of heparanase inhibitor. Bioorg.Med.Chem.Letts. 15 2295

If you know of a relevant reference for OGT 2115, please let us know.

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关键词: OGT 2115, OGT 2115 supplier, Antiangiogenic, Heparanase, inhibitors, inhibits, Antiangiogenics, Glycosylases, Carbohydrate, Metabolism, OGT2115, Cell, Adhesion, Molecules, 2710, Tocris Bioscience