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OLDA

Cat. No. 1641 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
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说明： Potent and selective endogenous TRPV1 agonist
别名： N-Oleoyldopamine
化学名： (9Z)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-9-octadecenamide
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for OLDA

OLDA is a potent endogenous vanilloid TRPV1 (VR1) receptor agonist (EC50 = 36 nM at hVR1) with low affinity for rCB1 receptors (Ki = 1.6 μM). Potently induces VR1-mediated thermal hyperalgesia in rats in vivo.

技术数据 for OLDA

分子量 417.63
公式 C26H43NO3
储存 Desiccate at -20°C
纯度 ≥98% (HPLC)
CAS Number 105955-11-1
PubChem ID 5282106
InChI Key QQBPLXNESPTPNU-KTKRTIGZSA-N
Smiles CCCCCCCC\C=C/CCCCCCCC(=O)NCCC1=CC=C(O)C(O)=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for OLDA

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 20.88 50
ethanol 20.88 50

制备储备液 for OLDA

以下数据基于产品分子量 417.63。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 4.79 mL 23.94 mL 47.89 mL
2.5 mM 0.96 mL 4.79 mL 9.58 mL
5 mM 0.48 mL 2.39 mL 4.79 mL
25 mM 0.1 mL 0.48 mL 0.96 mL

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产品说明书 for OLDA

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for OLDA

参考文献是支持产品生物活性的出版物。

Butelman et al (2004) Anitallodynic effects of loperamide and fen. against topical capsaicin-induced allodynia in unanesthetized primates. J.Pharmacol.Exp.Ther. 311 155 PMID: 15152028

Chu et al (2003) N-OleoylDA, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J.Biol.Chem. 278 13633 PMID: 12569099

If you know of a relevant reference for OLDA, please let us know.

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关键词: OLDA, OLDA supplier, Potent, selective, endogenous, TRPV1, agonists, Vanillioid, Receptors, VR1, TRPV, Channels, Transient, Receptor, Potential, N-Oleoyldopamine, 1641, Tocris Bioscience

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引用文献是使用了 Tocris 产品的出版物。

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