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Submit ReviewOrg 37684
说明： 5-HT2 agonist
化学名： (3S)-3-[(2,3--Dihydro-5-methoxy-1H-inden-4-yl)oxy]pyrrolidine hydrochloride
生物活性 for Org 37684
Org 37684 is an agonist of 5-HT2 receptors. Exhibits a rank order of potency of 5-HT2C >5-HT2B >5-HT2A (pEC50 values are 8.17, 7.96 and 7.11 respectively, in transfected CHO-K1 cells).
技术数据 for Org 37684
| 分子量 | 269.77 |
| 公式 | C14H19NO2.HCl |
| 储存 | Desiccate at RT |
| CAS Number | 213007-95-5 |
| PubChem ID | 9881884 |
| InChI Key | KJEAKWPQCIAVGR-MERQFXBCSA-N |
| Smiles | COC1=CC=C(CCC3)C3=C1O[C@H]2CCNC2.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Org 37684
参考文献 for Org 37684
参考文献是支持产品生物活性的出版物。
Porter et al (1999) Functional characterization of agonists at recombinant human 5-HT2A, 5-HT2B and 5-HT2C receptors in CHO-K1 cells. Br.J.Pharmacol. 128 13 PMID: 10498829
De Vry and Schreiber (2000) Effects of selected serotonin 5-HT1 and 5-HT2 receptor agonists on feeding behavior: possible mechanisms of action. Neurosci.Biobehav.Rev. 24 341 PMID: 10781694
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关键词: Org 37684, Org 37684 supplier, Org37684, 5-HT2, 5-HT2C, agonists, serotonergic, serotonin, Non-selective, 4797, Tocris Bioscience
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.