Oxotremorine sesquifumarate

Cat. No. 0843 3 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Muscarinic agonist

化学名： 1-[4-(1-Pyrrolidinyl)-2-butynyl]-2-pyrrolidinone sesquifumarate

纯度： ≥98% (HPLC)

引用文献 (3)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Oxotremorine sesquifumarate

Oxotremorine sesquifumarate is a muscarinic agonist.

技术数据 for Oxotremorine sesquifumarate

分子量	380.4
公式	C₁₂H₁₈N₂O.1.5C₄H₄O₄
储存	Store at RT
纯度	≥98% (HPLC)
CAS Number	17360-35-9
PubChem ID	6436473
InChI Key	WLYYOFJEBGHKEC-VQYXCCSOSA-N
Smiles	OC(=O)\C=C\C(O)=O.OC(=O)\C=C\C(O)=O.OC(=O)\C=C\C(O)=O.O=C1CCCN1CC#CCN1CCCC1.O=C1CCCN1CC#CCN1CCCC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Oxotremorine sesquifumarate

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	water	9.51	25
	DMSO	38.04	100

制备储备液 for Oxotremorine sesquifumarate

以下数据基于产品分子量 380.4。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.63 mL	13.14 mL	26.29 mL
5 mM	0.53 mL	2.63 mL	5.26 mL
10 mM	0.26 mL	1.31 mL	2.63 mL
50 mM	0.05 mL	0.26 mL	0.53 mL

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产品说明书 for Oxotremorine sesquifumarate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Oxotremorine sesquifumarate

参考文献是支持产品生物活性的出版物。

Fisher et al (1984) Differential stimulation in inositol phospholipid turnover in brain by analogs of oxotremorine. J.Neurochem. 43 1171 PMID: 6088696

Moroi-Fetters et al (1988) Muscarinic receptor-mediated phosphoinositide hydrolysis in the rat retina. J.Pharmacol.Exp.Ther. 246 553 PMID: 2841451

Merck Index 12 7085

If you know of a relevant reference for Oxotremorine sesquifumarate, please let us know.

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关键词: Oxotremorine sesquifumarate, Oxotremorine sesquifumarate supplier, Muscarinic, agonist, Receptors, Acetylcholine, ACh, Non-selective, Muscarinics, 0843, Tocris Bioscience

3 篇 Oxotremorine sesquifumarate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Oxotremorine sesquifumarate 的部分引用包括：

Deng et al (2013) Label-free cell phenotypic assessment of the biased agonism and efficacy of agonists at the endogenous muscarinic M3 receptors. J Pharmacol Toxicol Methods 68 323 PMID: 23933114

Bragança et al (2016) Ion Fluxes through KCa2 (SK) and Cav1 (L-type) Channels Contribute to Chronoselectivity of Adenosine A1 Receptor-Mediated Actions in Spontaneously Beating Rat Atria. Front Pharmacol 7 45 PMID: 27014060

Carneiro et al (2014) Activation of P2Y6 receptors increases the voiding frequency in anaesthetized rats by releasing ATP from the bladder urothelium. Br J Pharmacol 171 3404 PMID: 24697602

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