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Submit ReviewOxymetazoline hydrochloride
Discontinued Product
1142 has been discontinued.
View all Adrenergic α<sub>1</sub> Receptors products.
说明： α1A agonist
化学名： 3-[(4,5-Dihydro-1H-imidazol-2-yl)methyl]-6-(1,1-dimethylethyl)-2,4-dimethyl-phenol hydrochloride
纯度： ≥99% (HPLC)
生物活性 for Oxymetazoline hydrochloride
Partial α2A adrenoceptor agonist and α1A agonist. Agonist/antagonist activity at 5-HT receptors.
技术数据 for Oxymetazoline hydrochloride
| 分子量 | 296.84 |
| 公式 | C16H24N2O.HCl |
| 储存 | Store at RT |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 2315-02-8 |
| PubChem ID | 66259 |
| InChI Key | BEEDODBODQVSIM-UHFFFAOYSA-N |
| Smiles | Cl.CC1=C(CC2=NCCN2)C(C)=C(O)C(=C1)C(C)(C)C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Oxymetazoline hydrochloride
参考文献 for Oxymetazoline hydrochloride
参考文献是支持产品生物活性的出版物。
Bayorh et al (1997) Cardiovascular effects of oxymetazoline and UK14,304 in conscious and pithed rats. Clin.Exp.Hypertens. 19 445 PMID: 9140707
Horie et al (1995) Selectivity of the imidazoline α-adrenoceptor agonists (oxymetazoline and cirazoline) for human cloned α1-adrenoceptor subtypes. Br.J.Pharmacol. 116 1611 PMID: 8564227
Schoeffter et al (1991) Interaction of the α-adrenoceptor agonist oxymetazoline with serotonin 5-HT1A, 5-HT1B, 5-HT1C and 5-HT1D receptors. Eur.J.Pharmacol. 196 213 PMID: 1678720
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关键词: Oxymetazoline hydrochloride, Oxymetazoline hydrochloride supplier, α1A-adrenoceptor, alpha1A-adrenoceptor, a1a-adrenoceptor, agonists, alpha2A-adrenoceptor, a2a-adrenoceptor, partial, α1-adrenergic, alpha1-adrenergic, a1-Adrenergic, alpha2a-Adrenergic, a2a-Adrenergic, Receptors, Adrenergic, Alpha-1, Alpha-2, 1142, Tocris Bioscience
2 篇 Oxymetazoline hydrochloride 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Oxymetazoline hydrochloride 的部分引用包括：
Schihada et al (2018) A universal bioluminescence resonance energy transfer sensor design enables high-sensitivity screening of GPCR activation dynamics. Commun Biol 1 105 PMID: 30271985
Montgomery (2017) An Alpha-1A Adrenergic Receptor Agonist Prevents Acute dox. Cardiomyopathy in Male Mice. Plos One 12 e0168409 PMID: 28081170
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Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.