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PA Nic

Cat. No. 6700 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6700 has been discontinued.

View all Caged Nicotinic Compounds products.
说明： Caged nicotine; photoactivated by one-photon and two-photon excitation
化学名： (1S,2S)-1-((7-(Bis(carboxymethyl)amino)-2-oxo-2H-chromen-4-yl)methyl)-1-methyl-2-(pyridin-3-yl)pyrrolidin-1-ium ditrifluoroacetate
纯度： ≥98% (HPLC)
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for PA Nic

PA Nic is a coumarin-caged nicotine. Releases nicotine when exposed to 390 ± 10 nm wavelength light (λmax = 404 nm). Suitable for two-photon uncaging at <900 nm (Maximum two-photon cross-section at 810 nm). Extinction coefficient (ε) 17,400 M-1cm-1. Evokes nicotinic currents in mouse brain slices under one and two-photon activation conditions.

技术数据 for PA Nic

分子量 679.52
公式 C24H26N3O6.C2F3O2.C2HF3O2
储存 Store at -20°C
纯度 ≥98% (HPLC)
Smiles C[N@@+]1(CC2=CC(OC3=C2C=CC(N(CC(O)=O)CC(O)=O)=C3)=O)CCC[C@H]1C4=CC=CN=C4.OC(C(F)(F)F)=O.[O-]C(C(F)(F)F)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for PA Nic

参考文献是支持产品生物活性的出版物。

Banala et al (2018) Photoactivatable drugs for nicotinic optopharmacology. Nat.Methods 15 347 PMID: 29578537

Yan et al (2018) Nicotinic cholinergic receptors in VTA glutamate neurons modulate excitatory transmission. Cell Rep. 23 2236 PMID: 29791835

Arvin et al (2019) Probing nicotinic acetylcholine receptor function in mouse brain slices via laser flash photolysis of photoactivatable nicotine. J.Vis.Exp. 143 e58873 PMID: 30735191

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关键词: PA Nic, PA Nic supplier, PANic, caged, compounds, photoactivatable, nicotine, nicotinics, cholinergics, agonists, activators, nAChR, Nicotinic, Receptors, (Non-selective), Caged, Compounds, 6700, Tocris Bioscience

篇 PA Nic 的引用文献

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目前没有 PA Nic 的引用文献。

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