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Submit ReviewPACOCF3
说明： Phospholipase A2 inhibitor
别名： Palmityl trifluoromethyl ketone
化学名： 1,1,1-Trifluoro-2-heptadecanone
纯度： ≥99% (HPLC)
生物活性 for PACOCF3
PACOCF3 is a phospholipase A2 inhibitor. Can also alter Ca2+ signaling in renal tubular cells.
技术数据 for PACOCF3
| 分子量 | 308.43 |
| 公式 | C17H31F3O |
| 储存 | Desiccate at -20°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 141022-99-3 |
| PubChem ID | 4670 |
| InChI Key | MAHYXYTYTLCTQD-UHFFFAOYSA-N |
| Smiles | FC(F)(F)C(CCCCCCCCCCCCCCC)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for PACOCF3
参考文献 for PACOCF3
参考文献是支持产品生物活性的出版物。
Ackermann et al (1995) Inhibition of macrophage Ca2+-independent phospholipase A2 by bromoenol lactone and trifluoromethyl ketones. J.Biol.Chem. 270 445 PMID: 7814408
Jan et al (2000) Dual action of palmitoyl trifluoromethyl ketone (PACOCF3) on Ca2+ signaling: activation of extracellular Ca2+ influx and alteration of ATP- and bradykinin-induced Ca2+ responses in Madin Darby canine kidney cells. Arch.Toxicol. 74 447 PMID: 11097381
Lio et al (1996) Irreversible inhibition of Ca2+-independent phospholipase A2 by methyl arachidonyl fluorophosphonate. Biochim.Biophys.Acta 1302 55 PMID: 8695655
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关键词: PACOCF3, PACOCF3 supplier, Phospholipases, A2, inhibitors, inhibits, PLA2, Esterases, Palmityl, trifluoromethyl, ketone, 1460, Tocris Bioscience
3 篇 PACOCF3 的引用文献
引用文献是使用了 Tocris 产品的出版物。 PACOCF3 的部分引用包括：
Qiu et al (2014) GluA1 phosphorylation contributes to postsynaptic amplification of neuropathic pain in the insular cortex. J Neurosci 34 13505 PMID: 25274827
Potapova et al (2013) Caspases and p38 MAPK regulate endothelial cell adhesiveness for mesenchymal stem cells. J Neurosci 8 e73929 PMID: 24069252
Singaravelu et al (2006) Regulation of store-operated calcium entry by calcium-independent phospholipase A2 in rat cerebellar astrocytes. J Neurosci 26 9579 PMID: 16971542
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