Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewPALDA
说明： Endogenous lipid; potentiates effects of endovanilloids at TRPV1 receptors
别名： N-Palmitoyldopamine
化学名： N-[2-(3,4-Dihydroxyphenyl)ethyl]hexadecanamide
纯度： ≥98% (HPLC)
生物活性 for PALDA
Endogenous fatty acid dopamide that displays 'entourage' effects on endovanilloids NADA and anandamide. Inactive at TRPV1 and CB1 receptors (at concentrations up to 5 μM) and does not inhibit AMT or FAAH (IC50 > 25 μM). However, potentiates TRPV1-mediated effects of NADA; lowers EC50 from ~ 90 to ~ 30 nM.
技术数据 for PALDA
| 分子量 | 391.59 |
| 公式 | C24H41NO3 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 136181-87-8 |
| PubChem ID | 16759163 |
| InChI Key | TWJJFOWLTIEYFO-UHFFFAOYSA-N |
| Smiles | CCCCCCCCCCCCCCCC(=O)NCCC1=CC(O)=C(O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for PALDA
参考文献 for PALDA
参考文献是支持产品生物活性的出版物。
Chu et al (2003) N-OleoylDA, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J.Biol.Chem. 278 13633 PMID: 12569099
De Petrocellis et al (2004) Actions of two naturally occurring saturated N-acylDAs on transient receptor potential vanilloid 1 (TRPV1) channels. Br.J.Pharmacol. 143 251 PMID: 15289293
关键词: PALDA, PALDA supplier, Endogenous, lipid, potentiates, effects, endovanilloids, TRPV1, receptors, Vanillioid, Receptors, VR1, TRPV, TRP, Channels, Transient, Receptor, Potential, N-Palmitoyldopamine, 2203, Tocris Bioscience
PALDA 的评论
目前没有该产品的评论。 Be the first to review PALDA and earn rewards!
Have you used PALDA?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image