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说明： Negative control for PDD 00017238 (Cat. No. 7007)
化学名： 1-[(2,4-Dimethyl-5-thiazolyl)methyl]-2,3-dihydro-N-methyl-N-(1-methylcyclopropyl)-2-oxo-3-(1,2,4-thiadiazol-5-yl)-1H-benzimidazole-5-sulfonamide
纯度： ≥98% (HPLC)
生物活性 for PDD 00031705
PDD 00031705 is a negative control for PDD 00017238 (Cat. No. 7007).
技术数据 for PDD 00031705
| 分子量 | 490.62 |
| 公式 | C20H22N6O3S3 |
| 储存 | Store at -20°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 2032096-45-8 |
| PubChem ID | 123131658 |
| InChI Key | KWGUETFSHQZXMA-UHFFFAOYSA-N |
| Smiles | CN(S(=O)(C1=CC=C2N(C(N(C2=C1)C3=NC=NS3)=O)CC4=C(N=C(S4)C)C)=O)C5(CC5)C |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for PDD 00031705
参考文献 for PDD 00031705
参考文献是支持产品生物活性的出版物。
James et al (2016) First-in-class chemical probes against poly(ADP-ribose) glycohydrolase (PARG) inhibit DNA repair with differential pharmacology to Olaparib. ACS Chem.Biol. 11 3179 PMID: 27689388
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关键词: PDD 00031705, PDD 00031705 supplier, PDD00031705, poly, ADP, ribose, glycohydrolase, PARG, inhibitors, negative, controls, Poly(ADP)-ribose, Glycohydrolase, 7009, Tocris Bioscience
1 篇 PDD 00031705 的引用文献
引用文献是使用了 Tocris 产品的出版物。 PDD 00031705 的部分引用包括：
Craig A et al (2018) Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling. Sci Rep 8 2709 PMID: 29426911
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This poster summarizes the main epigenetic targets in cancer. The dysregulation of epigenetic modifications has been shown to result in oncogenesis and cancer progression. Unlike genetic mutations, epigenetic alterations are considered to be reversible and thus make promising therapeutic targets.