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Submit ReviewPentobarbital sodium salt enhances GABAergic activity. Pentobarbital is a short-acting barbiturate.
分子量 | 248.25 |
公式 | C11H17N2NaO3 |
储存 | Store at RT |
CAS Number | 57-33-0 |
PubChem ID | 14075609 |
InChI Key | QGMRQYFBGABWDR-UHFFFAOYSA-M |
Smiles | [Na+].CCCC(C)C1(CC)C(=O)NC([O-])=NC1=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Steinbach and Akk (2001) Modulation of GABAA receptor channel gating by pentobar. J.Physiol. 537 715 PMID: 11744750
关键词: Pentobarbital sodium salt, Pentobarbital sodium salt supplier, Pentobarbital, barbiturates, hypnotics, anticonvulsants, GABAergic, GABA, Miscellaneous, GABAB, Receptors, 4579, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Pentobarbital sodium salt 的部分引用包括:
Ying et al (2021) The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization. J Cell Mol Med 25 6709-6720 PMID: 34057287
Jost B et al (2021) In vivo Imaging of Retina and Choroid in Guinea Pigs. Front Med (Lausanne) 8 730494 PMID: 34926491
Yan et al (2016) MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis. Nat Commun 38 201 PMID: 27247228
Konstantin et al (2020) Disruption of Cholinergic Circuits as an Area for Targeted Drug Treatment of Alzheimer's Disease: In Vivo Assessment of Short-Term Plasticity in Rat Brain. Pharmaceuticals (Basel) 13 PMID: 33050228
Xueyu et al (2023) Upregulation of miR-144-3p alleviates Doxorubicin-induced heart failure and cardiomyocytes apoptosis via SOCS2/PI3K/AKT axis. Chem Biol Drug Des 101 24-39 PMID: 35730258
Jost B et al (2023) Intravitreal Short-Hairpin RNA Attenuated Adeno-Associated Virus-Induced Knockdown of Amphiregulin and Axial Elongation in Experimental Myopia. Invest Ophthalmol Vis Sci 64 11 PMID: 37040096
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Ian Martin, Norman Bowery and Susan Dunn, this review provides a history of the GABA receptor, as well as discussing the structure and function of the various subtypes and the clinical potential of receptor modulators; compounds available from Tocris are listed.