Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewPhenserine
说明： Cholinesterase inhibitor
化学名： (3aS,8aR)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol 5-(N-phenylcarbamate)
纯度： ≥98% (HPLC)
生物活性 for Phenserine
Physostigmine analog that inhibits acetylcholinesterase. Inhibits production of amyloid precursor protein (APP) and Aβ. Improves morris water maze performance of scopolamine-treated rats.
技术数据 for Phenserine
| 分子量 | 337.42 |
| 公式 | C20H23N3O2 |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 101246-66-6 |
| PubChem ID | 192706 |
| InChI Key | PBHFNBQPZCRWQP-QUCCMNQESA-N |
| Smiles | O=C(OC2=CC=C(N(C)[C@]4([H])[C@](C)3CCN4C)C3=C2)NC1=CC=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Phenserine
参考文献 for Phenserine
参考文献是支持产品生物活性的出版物。
Janas et al (2005) The cholinesterase inhibitor, phenserine, improves morris water maze performance of scopolamine-treated rats. Life Sci. 76 1073 PMID: 15620572
Utsuki et al (2006) Identification of novel small molecule inhibitors of amyloid precursor protein synthesis as a route to lower Alzheimer's disease amyloid-β peptide. J.Pharmacol.Exp.Ther. 318 855 PMID: 16690718
Klein (2007) Phenserine. Expert Opin.Investig.Drugs 16 1087 PMID: 17594192
按产品操作查看相关产品
关键词: Phenserine, Phenserine supplier, Cholinesterase, inhibitors, inhibits, AChE, Acetylcholinesterase, Esterases, Acetylcholine, Nicotinic, Receptors, nAChR, Muscarinic, Cholinesterases, Non-selective, Muscarinics, 2967, Tocris Bioscience
1 篇 Phenserine 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Phenserine 的部分引用包括：
Elgueta et al (2015) Acetylcholine induces GABA release onto rod bipolar cells through heteromeric nicotinic receptors expressed in A17 amacrine cells. Sci Rep 9 6 PMID: 25709566
Phenserine 的评论
目前没有该产品的评论。 Be the first to review Phenserine and earn rewards!
Have you used Phenserine?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Alzheimer's Disease Poster
Alzheimer's disease (AD) is a debilitating and progressive neurodegenerative disease and the most common cause of dementia, affecting approximately 30% of individuals aged over 85 years. This poster summarizes the cellular and molecular mechanisms of AD.