Physostigmine hemisulfate

Cat. No. 0622 6 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： Cholinesterase inhibitor

化学名： (3aS)-cis-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3-b]indol-5-ol methylcarbamate hemisulfate

纯度： ≥98% (HPLC)

引用文献 (6)

文献 (1)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for Physostigmine hemisulfate

Physostigmine hemisulfate is a cholinesterase inhibitor.

技术数据 for Physostigmine hemisulfate

分子量	324.39
公式	C₁₅H₂₁N₃O₂.½H₂SO₄
储存	Desiccate at RT
纯度	≥98% (HPLC)
CAS Number	64-47-1
PubChem ID	21872909
InChI Key	YYBNDIVPHIWTPK-UHFFFAOYSA-N
Smiles	OS(O)(=O)=O.CNC(=O)OC1=CC=C2N(C)C3N(C)CCC3(C)C2=C1.CNC(=O)OC1=CC=C2N(C)C3N(C)CCC3(C)C2=C1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for Physostigmine hemisulfate

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
溶解性	water	32.44	100

制备储备液 for Physostigmine hemisulfate

以下数据基于产品分子量 324.39。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.08 mL	15.41 mL	30.83 mL
5 mM	0.62 mL	3.08 mL	6.17 mL
10 mM	0.31 mL	1.54 mL	3.08 mL
50 mM	0.06 mL	0.31 mL	0.62 mL

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产品说明书 for Physostigmine hemisulfate

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Physostigmine hemisulfate

参考文献是支持产品生物活性的出版物。

Millard and Broomfield (1995) Anticholinesterases: medical applications of neurochemical principles. J.Neurochem 64 1909 PMID: 7722478

Merck Index 12 7540

If you know of a relevant reference for Physostigmine hemisulfate, please let us know.

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关键词: Physostigmine hemisulfate, Physostigmine hemisulfate supplier, Cholinesterase, inhibitors, inhibits, AChE, Acetylcholinesterase, Esterases, Acetylcholine, Nicotinic, Receptors, nAChR, Muscarinic, Non-selective, Muscarinics, Cholinesterases, 0622, Tocris Bioscience

6 篇 Physostigmine hemisulfate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Physostigmine hemisulfate 的部分引用包括：

Huchzermeyer et al (2013) Oxygen consumption rates during three different neuronal activity states in the hippocampal CA3 network. J Cereb Blood Flow Metab 33 263 PMID: 23168532

Lecrux et al (2017) Impact of Altered Cholinergic Tones on the Neurovascular Coupling Response to Whisker Stimulation. J Neurosci 37 1518 PMID: 28069927

Galow et al (2014) Energy substrates that fuel fast neuronal network oscillations. J Neurosci 8 398 PMID: 25538552

Parent et al (2015) Cholinergic and ghrelinergic receptors and KCNQ channels in the medial PFC regulate the expression of palatability. Proc Natl Acad Sci U S A 9 284 PMID: 26578914

Shin et al (2015) Muscarinic regulation of DA and glutamate transmission in the nucleus accumbens. Front Neurosci 112 8124 PMID: 26080439

Chiu and Castillo (2008) Input-specific plasticity at excitatory synapses mediated by endocannabinoids in the dentate gyrus. Neuropharmacology 54 68 PMID: 17706254

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