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(+)-Abscisic Acid

Cat. No. 6554 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

6554 has been discontinued.

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说明： Endogenous LANCL2 agonist
化学名： (2Z,4E)-5-[(1S)-1-Hydroxy-2,6,6-trimethyl-4-oxo-2-cyclohexen-1-yl]-3-methyl-2,4-pentadienoic acid
纯度： ≥98% (HPLC)
说明书
引用文献 (1)
评论
生物活性 技术数据 说明书 参考文献

生物活性 for (+)-Abscisic Acid

(+)-Abscisic Acid is an endogenous lanthionine synthetase C-like 2 (LANCL2) ligand. Stimulates glucose uptake by myocytes and pre-adipocytes in vitro, and by brown adipose tissue in vivo. Acts as a pro-inflammatory modulator of innate immune system cells. Stimulates proliferation of human mesenchymal and hematopoietic stem cells. Also used to control Cas9 via a RNA polymerase-based biosensor.

技术数据 for (+)-Abscisic Acid

分子量 264.32
公式 C15H20O4
储存 Store at -20°C
纯度 ≥98% (HPLC)
CAS Number 21293-29-8
PubChem ID 5280896
InChI Key JLIDBLDQVAYHNE-YKALOCIXSA-N
Smiles CC(/C=C/[C@]1(C(C)=CC(CC1(C)C)=O)O)=C/C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for (+)-Abscisic Acid

分析证书/产品说明书
化学品安全技术说明书

参考文献 for (+)-Abscisic Acid

参考文献是支持产品生物活性的出版物。

Carbo et al (2016) An N,N-Bis(benzimidazolylpicolinoyl)piperazine (BT-11): A novel lanthionine synthetase C-Like 2-based therapeutic for inflammatory bowel disease. J.Med.Chem. 59 10113 PMID: 27933891

Fresia et al (2016) G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2. Sci.Rep. 6 PMID: 27222287

Sturla et al (2017) Abscisic acid enhances glucose disposal and induces brown fat activity in adipocytes in vitro and in vivo. Biochim.Biophys.Acta. 1862 131 PMID: 27871880

Pu et al (2018) Multidimensional control of Cas9 by evolved RNA polymerase-based biosensors. ACS Chem.Biol. 13 431 PMID: 28809467

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关键词: (+)-Abscisic Acid, (+)-Abscisic Acid supplier, LANCL2, agonists, ligands, ABA, Abscisic, acid, phytophormone, Other, Synthases/Synthetases, CRISPR, Reagents, 6554, Tocris Bioscience

1 篇 (+)-Abscisic Acid 的引用文献

引用文献是使用了 Tocris 产品的出版物。 (+)-Abscisic Acid 的部分引用包括：

Pengli et al (2022) Engineering receptors in the secretory pathway for orthogonal signalling control. Nat Commun 13 7350 PMID: 36446786

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