(+)-SK&F 10047 hydrochloride

Cat. No. 1079 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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说明： σ₁ selective agonist

化学名： (2S,6S,11S)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(2-propenyl)-2,6-methano-3-benzazocin-8-ol hydrochloride

纯度： ≥98% (HPLC)

引用文献 (5)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for (+)-SK&F 10047 hydrochloride

(+)-SK&F 10047 hydrochloride is a prototypical σ₁ receptor agonist. Behaviorally active in animal models of memory and stress.

技术数据 for (+)-SK&F 10047 hydrochloride

分子量	293.84
公式	C₁₇H₂₃NO.HCl
储存	Desiccate at +4°C
纯度	≥98% (HPLC)
CAS Number	133005-41-1
PubChem ID	16759596
InChI Key	ZTGMHFIGNYXMJV-XSCGHNKWSA-N
Smiles	Cl.C[C@@H]1[C@@H]2CC3=CC=C(O)C=C3[C@@]1(C)CCN2CC=C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for (+)-SK&F 10047 hydrochloride

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	water	29.38	100
	DMSO	29.38	100

制备储备液 for (+)-SK&F 10047 hydrochloride

以下数据基于产品分子量 293.84。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	3.4 mL	17.02 mL	34.03 mL
5 mM	0.68 mL	3.4 mL	6.81 mL
10 mM	0.34 mL	1.7 mL	3.4 mL
50 mM	0.07 mL	0.34 mL	0.68 mL

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产品说明书 for (+)-SK&F 10047 hydrochloride

分析证书/产品说明书

化学品安全技术说明书

参考文献 for (+)-SK&F 10047 hydrochloride

参考文献是支持产品生物活性的出版物。

Kamei et al (1996) (+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress via DArgic systems linked to phenytoin-regulated σ₁ sites. Eur.J.Pharmacol. 309 149 PMID: 8874133

Matsuno et al (1995) Involvement of σ₁ receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats. Brain Res. 690 200 PMID: 8535837

Walker et al (1990) Sigma receptors: biology and function. Pharmacol.Rev. 42 355 PMID: 1964225

If you know of a relevant reference for (+)-SK&F 10047 hydrochloride, please let us know.

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