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Propofol

Cat. No. 0939 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

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化学名： 2,6-Diisopropylphenol
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引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for Propofol

Intravenous general anesthetic and hypnotic with a mode of action which includes potentiation of GABA-mediated inhibitory synaptic transmission, direct activation of the GABAA receptor and inhibition of glutamate receptor mediated excitatory synaptic transmission. Also potentiates P2X4 receptor-mediated currents in P2X4-HEK293 cells.

技术数据 for Propofol

分子量 178.27
公式 C12H18O
储存 Store at RT
CAS Number 2078-54-8
Smiles OC1=C(C(C)C)C=CC=C1C(C)C

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Propofol

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参考文献 for Propofol

参考文献是支持产品生物活性的出版物。

Nadeson and Goodchild (1997) Antinociceptive properties of PropF.: involvement of spinal cord γ-aminobutyric acidA receptors. J.Pharmacol.Exp.Ther. 282 1181 PMID: 9316824

Orser et al (1995) Inhibition by PropF. (2,6-di-isopropylphenol) of the N-MthD.-aspartate subtype of glutamate receptor in cultured hippocampal neurones. Br.J.Pharmacol. 116 1761 PMID: 8528557

Takahashi et al (1994) The effects of PropF. and enfl. on single calcium channel currents of guinea-pig isolated ventricular myocytes. Br.J.Pharmacol. 111 1147 PMID: 8032601

Tomioka et al (2000) PropF. potentiates ATP-activated currents of recombinant P2X4 receptor channels expressed in human embryonic kidney 293 cells. Neurosci.Lett. 284 167 PMID: 10773425

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关键词: Propofol, Propofol supplier, , Tocris Bioscience

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