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说明： Metabolite
化学名： 1,2,3,4-Tetrahydro-4-oxo-N-(phenylmethyl)-2-thioxo-3-[3-(trifluoromethyl)phenyl]-7-quinazolinecarboxamide
纯度： ≥98% (HPLC)
生物活性 for Qc 1
Qc 1 is a reversible, non-competitive inhibitor of threonine dehydrogenase (TDH) (IC50 ~500 nM). Induces autophagy and inhibits cell proliferation in mouse embryonic stem (ES) cells.
技术数据 for Qc 1
| 分子量 | 455.45 |
| 公式 | C23H16F3N3O2S |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 403718-45-6 |
| PubChem ID | 5000754 |
| InChI Key | IFNVTSPDMUUAFY-UHFFFAOYSA-N |
| Smiles | O=C(N2C3=CC(C(F)(F)F)=CC=C3)C1=CC=C(C(NCC4=CC=CC=C4)=O)C=C1NC2=S |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Qc 1
参考文献 for Qc 1
参考文献是支持产品生物活性的出版物。
Alexander et al (2011) Targeted killing of a mammalian cell based upon its specialized metabolic state. Proc.Natl.Acad.Sci.USA 108 15828 PMID: 21896756
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关键词: Qc 1, Qc 1 supplier, Qc1, threonine, dehydrogenase, inhibitors, inhibits, TDH, Other, Dehydrogenases, 5055, Tocris Bioscience
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*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
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