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说明： Endogenous NMDA agonist and transmitter candidate
化学名： Pyridine-2,3-dicarboxylic acid
生物活性 for Quinolinic acid
Quinolinic acid is an endogenous NMDA agonist and transmitter candidate. May distinguish between NMDA receptor subtypes.
技术数据 for Quinolinic acid
| 分子量 | 167.12 |
| 公式 | C7H5NO4 |
| 储存 | Store at RT |
| CAS Number | 89-00-9 |
| PubChem ID | 1066 |
| InChI Key | GJAWHXHKYYXBSV-UHFFFAOYSA-N |
| Smiles | OC(=O)C1=C(N=CC=C1)C(O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Quinolinic acid
参考文献 for Quinolinic acid
参考文献是支持产品生物活性的出版物。
Monaghan and Beaton (1991) Quinolinate differentiates between forebrain and cerebellar NMDA receptors. Eur.J.Pharmacol. 194 123 PMID: 1676371
Prada de Carvalho et al (1996) The endogenous agonist quinolinic acid and the non-endogenous homoquinolinic acid discriminate between NMDAR2 receptor subunits. Neurochem.Int. 28 445 PMID: 8740453
Stone and Burton (1988) NMDA receptors and ligands in the vertebrate CNS. Prog.Neurobiol. 30 333 PMID: 2830636
Stone and Perkins (1981) Quinolinic acid: a potent endogenous excitant at amino acid receptors in the rat CNS. Eur.J.Pharmacol. 72 411 PMID: 6268428
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关键词: Quinolinic acid, Quinolinic acid supplier, agonists, Transmitter, candidate, Glutamate, NMDA, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0225, Tocris Bioscience
1 篇 Quinolinic acid 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Quinolinic acid 的部分引用包括：
Tsutsui-Kimura et al (2015) Milnacipran remediates impulsive deficits in rats with lesions of the ventromedial prefrontal cortex. Nat Commun 18 PMID: 25522418
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