Rac1 Inhibitor W56

Discontinued Product

2221 has been discontinued.

View all Rho GTPases products.
说明: Selective inhibitor of Rac1-GEF interaction
说明书
引用文献 (4)
评论

生物活性 for Rac1 Inhibitor W56

Rac1 Inhibitor W56 is a peptide comprising residues 45-60 of the guanine nucleotide exchange factor (GEF) recognition/activation site of Rac1; selectively inhibits Rac1 interaction with Rac1-specific GEFs TrioN, GEF-H1 and Tiam1.

Control Peptide also available.

技术数据 for Rac1 Inhibitor W56

分子量 1671.93
公式 C74H117N19O23S
序列 MVDGKPVNLGLWDTAG
储存 Desiccate at -20°C
CAS Number 1095179-01-3
PubChem ID 90488750
InChI Key IRORVMNZPUKWEX-YRMQSWGASA-N
Smiles [H]N[C@@H](CCSC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)NCC(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Rac1 Inhibitor W56

分析证书/产品说明书
选择另一批次:

参考文献 for Rac1 Inhibitor W56

参考文献是支持产品生物活性的出版物。

Gao et al (2001) Trp56 of Rac1 specifies interaction with a subset of guanine nucleotide exchange factors. J.Biol.Chem. 276 47530 PMID: 11595749

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Rho GTPase Inhibitors

关键词: Rac1 Inhibitor W56, Rac1 Inhibitor W56 supplier, Selective, inhibitors, inhibits, Rac1-GEF, interaction, GTPases, G, Proteins, Small, Rho, 2221, Tocris Bioscience

4 篇 Rac1 Inhibitor W56 的引用文献

引用文献是使用了 Tocris 产品的出版物。 Rac1 Inhibitor W56 的部分引用包括:

Ikram et al (2018) Co-targeting of Tiam1/Rac1 and Notch ameliorates chemoresistance against dox. in a biomimetic 3D lymphoma model. Oncotarget 9 2058 PMID: 29416753

Zeineddine et al (2015) SOD1 protein aggregates stimulate macropinocytosis in neurons to facilitate their propagation. Am J Physiol Lung Cell Mol Physiol 10 57 PMID: 26520394

Kruppa et al (2018) Myosin VI-Dependent Actin Cages Encapsulate Parkin-Positive Damaged Mitochondria. Dev Cell 44 484 PMID: 29398621

Bessa et al (2019) Subverted regulation of Nox1 NADPH oxidase-dependent oxidant generation by protein disulfide isomerase A1 in colon carcinoma cells with overactivated KRas. Cell Death Dis 10 143 PMID: 30760703


Rac1 Inhibitor W56 的评论

目前没有该产品的评论。 Be the first to review Rac1 Inhibitor W56 and earn rewards!

Have you used Rac1 Inhibitor W56?

Submit a review and receive an Amazon gift card.

$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review