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View all Histamine H<sub>2</sub> Receptors products.Ranitidine hydrochloride is a potent, selective and competitive histamine H2 receptor antagonist (pA2 = 6.95 - 7.2). Inhibits gastric acid secretion induced by histamine, pentagastrin, bethanecol and food in vivo. Also inhibits aspirin-induced gastric lesions.
分子量 | 350.86 |
公式 | C13H22N4O3S.HCl |
储存 | Desiccate at +4°C |
纯度 | ≥99% (HPLC) |
CAS Number | 66357-59-3 |
PubChem ID | 657344 |
InChI Key | GGWBHVILAJZWKJ-CHHCPSLASA-N |
Smiles | Cl[H].CN\C(NCCSCC1=CC=C(CN(C)C)O1)=C\N(=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Daly et al (1981) Some in vitro and in vivo actions of the new histamine H2-receptor antagonist, ranitidine. Br.J.Pharmacol. 72 49 PMID: 6112034
Daly et al (1981) Antagonism of vasodepressor and gastric secretory responses to histamine by the H2-receptor antagonists, ranitidine and cimetidine, in the anaesthetized dog. Br.J.Pharmacol. 72 55 PMID: 6112035
Brittain and Daly (1981) A review of the animal pharmacology of ranitidine - a new, selective histamine H2-antagonist. Scand.J.Gastroenterol.Suppl. 69 1
关键词: Ranitidine hydrochloride, Ranitidine hydrochloride supplier, Selective, H2, antagonists, receptors, histamine, histaminergic, h2, antagonist, Histamine, Receptors, 1967, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Ranitidine hydrochloride 的部分引用包括:
Kwiatkowski et al (2013) Coordination of distinct but interacting rhythmic motor programs by a modulatory projection neuron using different co-transmitters in different ganglia. J Exp Biol 216 1827 PMID: 23393282
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