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Submit ReviewRepSox is an ancillary Material Grade version of product RepSox (Cat. No. 3742). Suitable for use as an ancillary reagent in the further manufacturing of cell therapies.
Find out more about our Ancillary Material Grade product range.
分子量 | 287.32 |
公式 | C17H13N5 |
储存 | Store at 2-8°C |
纯度 | ≥99% |
CAS Number | 446859-33-2 |
InChI Key | LBPKYPYHDKKRFS-UHFFFAOYSA-N |
Smiles | CC1=NC(C2=NNC=C2C3=NC4=CC=CN=C4C=C3)=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
If you know of a relevant reference for RepSox, please let us know.
关键词: RepSox, RepSox supplier, Ancillary, Material, Grade, potent, inhibitors, inhibits, TGF-betaRI, TGF-beta, TGFbRI, TGFbR1, tgf-b1, ALK5, Transforming,Growth, Factors, Beta, stem, cells, E-616452, SJN2511, SJN, 2511, Stem, Cell, Reprogramming, manufacturing, gene, cell, therapies, GMP, Inhibitor, II, Small, Molecules, TB3742-RMU, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 RepSox 的部分引用包括:
Mishra et al (2022) Improved loss-of-function CRISPR-Cas9 genome editing in human cells concomitant with inhibition of TGF-beta signaling. Mol.Ther.Nucleic Acids 28 202 PMID: 35402072
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Stem cells have potential as a source of cells and tissues for research and treatment of disease. This poster summarizes some key protocols demonstrating the use of small molecules across the stem cell workflow, from reprogramming, through self-renewal, storage and differentiation to verification. Advantages of using small molecules are also highlighted.