Resiniferatoxin

Name: Resiniferatoxin
Brand: Tocris Bioscience
SKU: 1137

Cat. No. 1137 5 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1137 has been discontinued.

View all TRPV Channels products.

说明： Potent vanilloid receptor agonist

化学名： 4-Hydroxy-3-methoxy-[(2S,3aR,3bS,6aR,9aR,9bR,10R,11aR)-3a,3b,6,6a,9a,10,11,11a-octahydro-6a-hydroxy-8,10-dimethyl-11a-(1-methylethenyl)-7-oxo-2-(phenylmethyl)-7H-2,9b-epoxyazuleno[5,4-e]-1,3-benzodioxol-5-yl]benzeneacetate

纯度： ≥98% (HPLC)

说明书

引用文献 (5)

生物活性技术数据说明书参考文献

生物活性 for Resiniferatoxin

Potent analog of capsaicin that is an agonist at vanilloid receptors (K_i = 43 pM). Like capsaicin, it acts as a selective modulator of primary afferent neurons.

技术数据 for Resiniferatoxin

分子量	628.72
公式	C₃₇H₄₀O₉
储存	Desiccate at -20°C
纯度	≥98% (HPLC)
CAS Number	57444-62-9
PubChem ID	5702546
InChI Key	DSDNAKHZNJAGHN-MXTYGGKSSA-N
Smiles	O=C1C(C)=C[C@]2([H])[C@@](O)1CC(COC(CC5=CC(OC)=C(O)C=C5)=O)=C[C@]3([H])[C@@](O6)2[C@H](C)C[C@@]4([C@@](C)=C)[C@@]([H])3O[C@]6(CC7=CC=CC=C7)O4

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Resiniferatoxin

分析证书/产品说明书

化学品安全技术说明书

参考文献 for Resiniferatoxin

参考文献是支持产品生物活性的出版物。

Acs et al (1996) Distinct structure-activity relations for stimulation of ⁴⁵Ca uptake and for high affinity binding in cultured rat dorsal root ganglion neurons and dorsal root ganglion membranes. Brain Res.Mol.Brain Res. 35 173 PMID: 8717353

Szolcsanyi et al (1990) Resiniferatoxin: an ultrapotent selective modulator of capsaicin-sensitive primary afferent neurons. J.Pharmacol.Exp.Ther. 255 923 PMID: 2243359

Winter et al (1990) Cellular mechanism of action of resiniferatoxin: a potent sensory neuron excitotoxin. Brain Res. 520 131 PMID: 2169951

按标靶查看相关产品

按产品操作查看相关产品

查看全部 TRPV Channel Agonists

关键词: Resiniferatoxin, Resiniferatoxin supplier, Ultrapotent, vanilloid, receptor, agonist, Vanillioid, Receptors, VR1, TRPV, TRP, Channels, Transient, Receptor, Potential, 1137, Tocris Bioscience