RHC 80267

Cat. No. 1842 4 篇引用文献提交评论说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Pricing	Availability		Qty

说明： Diacylglycerol lipase inhibitor

别名： U 57908

化学名： O,O'-[1,6-Hexanediylbis(iminocarbonyl)]dioxime cyclohexanone

纯度： ≥95% (HPLC)

引用文献 (4)

生物活性技术数据溶解性计算器说明书参考文献

生物活性 for RHC 80267

RHC 80267 is an inhibitor of diacylglycerol lipase (IC₅₀ values are 1.1 and 4 μM in rat cardiac myocytes and canine platelets respectively). Weakly inhibits phospholipases C and A₂. Potentiates acetylcholine evoked relaxation in mesenteric arteries by the inhibition of cholinesterase activity (IC₅₀ = 4 μM).

技术数据 for RHC 80267

分子量	394.51
公式	C₂₀H₃₄N₄O₄
储存	Store at +4°C
纯度	≥95% (HPLC)
CAS Number	83654-05-1
PubChem ID	5063
InChI Key	RXSVYGIGWRDVQC-UHFFFAOYSA-N
Smiles	O=C(NCCCCCCNC(O/N=C2\CCCCC2)=O)O/N=C1CCCCC/1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for RHC 80267

	溶剂	最高浓度 mg/mL	最高浓度 mM
溶解性
	DMSO	39.45	100
	ethanol	39.45	100

制备储备液 for RHC 80267

以下数据基于产品分子量 394.51。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

浓度/溶剂体积/质量	1 mg	5 mg	10 mg
1 mM	2.53 mL	12.67 mL	25.35 mL
5 mM	0.51 mL	2.53 mL	5.07 mL
10 mM	0.25 mL	1.27 mL	2.53 mL
50 mM	0.05 mL	0.25 mL	0.51 mL

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.

Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Reconstitution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Concentration 1

Volume 1

Concentration 2

Volume 2

产品说明书 for RHC 80267

分析证书/产品说明书

化学品安全技术说明书

参考文献 for RHC 80267

参考文献是支持产品生物活性的出版物。

Ghisdal et al (2005) The diacylglycerol lipase inhibitor RHC-80267 potentiates the relaxation to acetylcholine in rat mesenteric artery by anti-cholinesterase action. Eur.J.Pharmacol. 517 97 PMID: 15958263

Sutherland and Amin (1982) Relative activities of rat and dog platelet phospholipase A₂ and diglyceride lipase. J.Biol.Chem. 257 14006 PMID: 7142192

Suzuki et al (2002) Effects of RHC-80267, an inhibitor of diacylglycerol lipase, on excitation of circular smooth muscle of the guinea-pig gastric antrum. J.Smooth Muscle Res. 38 153 PMID: 12713022

If you know of a relevant reference for RHC 80267, please let us know.

按标靶查看相关产品

按产品操作查看相关产品

查看全部 Other Lipid Metabolism Inhibitors

关键词: RHC 80267, RHC 80267 supplier, Diacylglycerol, lipases, inhibitors, inhibits, PLC, PLA2, Phospholipases, C, A, Esterases, Lipid, Metabolism, DAGL, RHC80267, U57908, U, 57908, Lipases, Phospholipase, Other, 1842, Tocris Bioscience