(RS)-2-Hydroxyglutaric acid disodium salt

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说明: Metabolite
化学名: (RS)-2-Hydroxypentanedioic acid disodium salt
说明书
引用文献
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文献 (2)

生物活性

(RS)-2-Hydroxyglutaric acid disodium salt is an oncometabolite with R- and S- enantiomers overproduced in the neurometabolic disease 2-hydroxyglutaric aciduria (2-HGA).

技术数据

分子量 192.08
公式 C5H6Na2O5
储存 Store at -20°C
CAS Number 40951-21-1
PubChem ID 134081824
InChI Key DZHFTEDSQFPDPP-UHFFFAOYSA-L
Smiles OC(C(O[Na])=O)CCC(O[Na])=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
water 19.21 100

制备储备液

以下数据基于产品分子量 192.08。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
1 mM 5.21 mL 26.03 mL 52.06 mL
5 mM 1.04 mL 5.21 mL 10.41 mL
10 mM 0.52 mL 2.6 mL 5.21 mL
50 mM 0.1 mL 0.52 mL 1.04 mL

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参考文献

参考文献是支持产品生物活性的出版物。

Du and Hu (2021) The roles of 2-Hydroxyglutarate. Front.Cell Dev.Biol. 9 651317 PMID: 33842477


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关键词: (RS)-2-Hydroxyglutaric acid disodium salt, (RS)-2-Hydroxyglutaric acid disodium salt supplier, 2-HG, D-2HG, L-2HG, DL-HG, oncometabolite, 2-HGA, 2-hydroxyglutaric, aciduria, Other, Dehydrogenases, 6122, Tocris Bioscience

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