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(RS)-3,4-DCPG

Cat. No. 1394 1 次引用 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1394 has been discontinued.

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说明： Potent systemically active anticonvulsant. Racemate of (R)-3,4,-DCPG (Cat. No. 1395)
化学名： (RS)-3,4-Dicarboxyphenylglycine
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论
文献 (1)
生物活性 技术数据 说明书 参考文献

生物活性 for (RS)-3,4-DCPG

(RS)-3,4-DCPG is a systemically active anticonvulsant that is 30-100-fold more potent in vivo than the separate enantiomers (S)-3,4-DCPG or (R)-3,4,-DCPG.

S-enantiomer and R-enantiomer also available.

技术数据 for (RS)-3,4-DCPG

分子量 239.18
公式 C10H9NO6
储存 Desiccate at RT
纯度 ≥99% (HPLC)
CAS Number 176796-64-8
PubChem ID 3313698
InChI Key IJVMOGKBEVRBPP-UHFFFAOYSA-N
Smiles NC(C(O)=O)C1=CC=C(C(O)=O)C(=C1)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for (RS)-3,4-DCPG

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for (RS)-3,4-DCPG

参考文献是支持产品生物活性的出版物。

Moldrich et al (2001) Anticonvulsant activity of 3,4-dicarboxyphenylglycines in DBA/2 mice. Neuropharmacology 40 732 PMID: 11311902

Thomas et al (1997) Dicarboxyphenylglycines antagonize AMPA- but not kainate-induced depolarizations in neonatal rat motoneurones. Eur.J.Pharmacol. 338 111 PMID: 9455991

Thomas et al (1998) Pharmacological differentiation of kainate receptors on neonatal rat spinal motoneurones and dorsal roots. Neuropharmacology 37 1223 PMID: 9849660

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关键词: (RS)-3,4-DCPG, (RS)-3,4-DCPG supplier, Potent, systemically, active, anticonvulsant, Racemate, Glutamate, Ionotropic, Non-Selective, iGlur, Receptors, Group, III, mGluR8, mGlu8, Metabotropic, antagonists, Non-selective, (Metabotropic), 1394, Tocris Bioscience

1 篇 (RS)-3,4-DCPG 的引用文献

引用文献是使用了 Tocris 产品的出版物。 (RS)-3,4-DCPG 的部分引用包括：

Gosnell et al (2011) mGluR8 modulates excitatory transmission in the bed nucleus of the stria terminalis in a stress-dependent manner. Neuropsychopharmacology 36 1599 PMID: 21451497

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