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Submit Review(RS)-AMPA hydrobromide
说明： Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169)
化学名： (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide
纯度： ≥99% (HPLC)
生物活性 for (RS)-AMPA hydrobromide
(RS)-AMPA hydrobromide is a more water soluble hydrobromide salt of (RS)-AMPA (Cat. No. 0169).
技术数据 for (RS)-AMPA hydrobromide
| 分子量 | 267.08 |
| 公式 | C7H10N2O4.HBr |
| 储存 | Desiccate at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 171259-81-7 |
| PubChem ID | 11957558 |
| InChI Key | KUAHVIUZGLGASU-UHFFFAOYSA-N |
| Smiles | Br.CC1=C(CC(N)C(O)=O)C(O)=NO1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for (RS)-AMPA hydrobromide
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 2.67 | 10 温和加热 |
制备储备液 for (RS)-AMPA hydrobromide
以下数据基于产品分子量 267.08。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.44 mL | 187.21 mL | 374.42 mL |
| 0.5 mM | 7.49 mL | 37.44 mL | 74.88 mL |
| 1 mM | 3.74 mL | 18.72 mL | 37.44 mL |
| 5 mM | 0.75 mL | 3.74 mL | 7.49 mL |
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产品说明书 for (RS)-AMPA hydrobromide
参考文献 for (RS)-AMPA hydrobromide
参考文献是支持产品生物活性的出版物。
Honore et al (1982) The binding of 3H-AMPA, a structural analogue of glutamic acid, to rat brain membranes. J.Neurochem. 38 173 PMID: 6125564
Krogsgaard-Larsen et al (1980) New class of glutamate agonist structurally related to ibotenic acid. Nature 284 64 PMID: 6101908
Ko et al (2021) Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19. Viruses 13 PMID: 33918958
If you know of a relevant reference for (RS)-AMPA hydrobromide, please let us know.
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关键词: (RS)-AMPA hydrobromide, (RS)-AMPA hydrobromide supplier, water, soluble, Glutamate, AMPA, Receptors, iGlur, Ionotropic, 1074, Tocris Bioscience
5 篇 (RS)-AMPA hydrobromide 的引用文献
引用文献是使用了 Tocris 产品的出版物。 (RS)-AMPA hydrobromide 的部分引用包括：
Iskandrani et al (2015) Impact of subanesthetic doses of KA on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons. J Neurosci 29 792 PMID: 25759403
Wasling et al (2012) AMPA receptor activation causes silencing of AMPA receptor-mediated synaptic transmission in the developing hippocampus. PLoS One 7 e34474 PMID: 22485173
Pierrot et al (2019) Sex-regulated gene dosage effect of PPARα on synaptic plasticity. Life Sci Alliance 2 PMID: 30894406
Chanda et al (2013) Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation. J Psychopharmacol 110 16622 PMID: 24046374
Goo et al (2017) Activity-dependent trafficking of lysosomes in dendrites and dendritic spines. J Cell Biol 216 2499 PMID: 28630145
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