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Discontinued Product
1220 has been discontinued.
View all Glutamate (Metabotropic) Group III Receptors products.
说明： Potent and selective mGlu8 agonist
化学名： (RS)-4-Phosphonophenylglycine
生物活性 for (RS)-PPG
(RS)-PPG is a potent and selective group III metabotropic glutamate receptor agonist, with approximately 25-fold preference for hmGlu8; anticonvulsant and neuroprotective in vivo.
技术数据 for (RS)-PPG
| 分子量 | 231.14 |
| 公式 | C8H10NO5P |
| 储存 | Store at RT |
| CAS Number | 120667-15-4 |
| PubChem ID | 4545574 |
| InChI Key | JRQRKFDFHAPMGQ-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)C1=CC=C(P(O)(O)=O)C=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for (RS)-PPG
参考文献 for (RS)-PPG
参考文献是支持产品生物活性的出版物。
Bigge et al (1989) Exploration of phenyl-spaced 2-amino-(5,9)-phosphonoalkanoic acids as competitive N-MthD.-aspartic acid antagonists. J.Med.Chem. 32 1580 PMID: 2544728
Gasparini et al (1999) (R,S)-4-Phosphonophenylglycine, a potent and selective group III metabotropic glutamate receptor agonist, is anticonvulsive and neuroprotective in vivo. J.Pharmacol.Exp.Ther. 289 1678 PMID: 10336568
Flor et al (1998) Neuroprotection in vitro and in vivo by (R,S)-PPG, a potent and selective group III metabotropic glutamate receptor agonist. Soc.Neurosci.Abstr. 24 431.11
关键词: (RS)-PPG, (RS)-PPG supplier, Potent, selective, mGlu8, mGluR8, agonist, Group, III, Receptors, Glutamate, Metabotropic, (Metabotropic), 1220, Tocris Bioscience
1 篇 (RS)-PPG 的引用文献
引用文献是使用了 Tocris 产品的出版物。 (RS)-PPG 的部分引用包括：
Kammermeier (2015) Constitutive activity of metabotropic glutamate receptor 7. Neuropharmacology 16 17 PMID: 25881041
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Metabotropic Glutamate Receptors Scientific Review
Written by Francine Acher, this review discusses the pharmacology and therapeutic potential of mGlu receptors, and the compounds acting upon them; compounds available from Tocris are listed.
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