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Submit Review(RS)-(Tetrazol-5-yl)glycine
说明： Highly potent NMDA agonist
纯度： ≥98% (HPLC)
生物活性 for (RS)-(Tetrazol-5-yl)glycine
(RS)-(Tetrazol-5-yl)glycine is a potent NMDA receptor agonist, approximately 20 times more active than NMDA.
技术数据 for (RS)-(Tetrazol-5-yl)glycine
| 分子量 | 143.1 |
| 公式 | C3H5N5O2 |
| 储存 | Store at RT |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 138199-51-6 |
| PubChem ID | 126383 |
| InChI Key | UKBRUIZWQZHXFL-UHFFFAOYSA-N |
| Smiles | NC(C(O)=O)C1=NN=NN1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性数据 for (RS)-(Tetrazol-5-yl)glycine
| 溶剂 | 最高浓度 mg/mL | 最高浓度 mM | |
|---|---|---|---|
| 溶解性 | |||
| water | 50 |
制备储备液 for (RS)-(Tetrazol-5-yl)glycine
以下数据基于产品分子量 143.1。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 浓度/溶剂体积/质量 | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.5 mM | 13.98 mL | 69.88 mL | 139.76 mL |
| 2.5 mM | 2.8 mL | 13.98 mL | 27.95 mL |
| 5 mM | 1.4 mL | 6.99 mL | 13.98 mL |
| 25 mM | 0.28 mL | 1.4 mL | 2.8 mL |
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产品说明书 for (RS)-(Tetrazol-5-yl)glycine
参考文献 for (RS)-(Tetrazol-5-yl)glycine
参考文献是支持产品生物活性的出版物。
Arnt et al (1995) Diffentiation of in vivo effects of AMPA and NMDA receptor ligands using drug discrimination methods and convulsant/anticonvulsant activity. Eur.J.Pharmacol. 285 289 PMID: 8575516
Moroni et al (1995) NMDA receptor heterogeneity in mammalian tissues: focus on two agonists, (2S,3R,4S)cyclopropylglutamate and the sulfate ester of 4-hydroxy-(S)-pipecolic acid. Naunyn Schmiedebergs Arch.Pharmacol. 351 371 PMID: 7543185
Schoepp et al (1991) D,L-(Tetrazol-5-yl)glycine a novel and highly potent NMDA receptor agonist. Eur.J.Pharmacol. 203 237 PMID: 1686860
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关键词: (RS)-(Tetrazol-5-yl)glycine, (RS)-(Tetrazol-5-yl)glycine supplier, potent, NMDA, receptor, agonists, Glutamate, Receptors, N-Methyl-D-Aspartate, iGluR, Ionotropic, 0312, Tocris Bioscience
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