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RU 24969 hemisuccinate

Cat. No. 0912 1 次引用 1 条评论 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）
Pricing Availability   Qty
说明： 5-HT1A and 5-HT1B agonist
化学名： 5-Methoxy-3-(1,2,5,6-tetrahydro-4-pyridinyl)-1H-indole hemisuccinate
纯度： ≥99% (HPLC)
说明书
引用文献 (1)
评论 (1)
文献 (3)
生物活性 技术数据 溶解性 计算器 说明书 参考文献

生物活性 for RU 24969 hemisuccinate

RU 24969 hemisuccinate is a potent 5-HT1A/1B and moderate 5-HT2C agonist that may also release 5-HT. Centrally active following systemic administration.

技术数据 for RU 24969 hemisuccinate

分子量 287.34
公式 C14H16N2O.½C4H6O4
储存 Store at RT
纯度 ≥99% (HPLC)
CAS Number 66611-27-6
PubChem ID 3050530
InChI Key BNYJLRQAWCQJOM-UHFFFAOYSA-N
Smiles OC(=O)CCC(O)=O.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1.COC1=CC=C2NC=C(C2=C1)C1=CCNCC1

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

溶解性数据 for RU 24969 hemisuccinate

溶剂 最高浓度 mg/mL 最高浓度 mM
溶解性
DMSO 14.37 50
water 8.62 30

制备储备液 for RU 24969 hemisuccinate

以下数据基于产品分子量 287.34。 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

选择批次从而根据批次分子量重新计算:
浓度/溶剂体积/质量 1 mg 5 mg 10 mg
0.5 mM 6.96 mL 34.8 mL 69.6 mL
2.5 mM 1.39 mL 6.96 mL 13.92 mL
5 mM 0.7 mL 3.48 mL 6.96 mL
25 mM 0.14 mL 0.7 mL 1.39 mL

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产品说明书 for RU 24969 hemisuccinate

分析证书/产品说明书
选择另一批次：
化学品安全技术说明书

参考文献 for RU 24969 hemisuccinate

参考文献是支持产品生物活性的出版物。

Gudermann et al (1993) Human S31 serotonin receptor clone encodes a 5-hydroxytryptamine1E-like serotonin receptor. Mol.Pharmacol. 43 412 PMID: 8450834

Tomkins and O'Neill (2000) Effect of 5-HT1B receptor ligands on self-administration of ethanol in an operant procedure in rats. Pharmacol.Biochem.Behav. 66 129 PMID: 10837852

Guillaume et al (1987) Synthesis of 3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles and study of their serotonergic and antiDArgic properties. Eur.J.Med.Chem. 22 33

If you know of a relevant reference for RU 24969 hemisuccinate, please let us know.

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关键词: RU 24969 hemisuccinate, RU 24969 hemisuccinate supplier, 5-HT1B/1A, agonists, Serotonin, Receptors, RU24969, hemisuccinate, C14H16N2O.0.5C4H6O4, 5-HT1A, 0912, Tocris Bioscience

1 篇 RU 24969 hemisuccinate 的引用文献

引用文献是使用了 Tocris 产品的出版物。 RU 24969 hemisuccinate 的部分引用包括：

Lawson et al (2016) Effects of oxyt. on Serotonin 1B Agonist-induced Autism-like Behavior in Mice Behavioural Brain Research 314 52 PMID: 27439030

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RU 24969 hemisuccinate 的评论

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5-HT1B agonist-induced social and attention deficits in mice.
By Anonymous on 05/09/2020
分析类型： In Vivo
种属： Mouse
细胞系/组织： brain

Drug treatment 0 or 10 mg/kg RU24969

PMID: 27439030 参考文献
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