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Submit ReviewRuBi-5-HT
说明： RuBi-caged serotonin
化学名： (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-5-hydroxytryptamine ruthenium(2+) dihexafluorophosphate complex
生物活性 for RuBi-5-HT
RuBi-caged version of serotonin (Cat. No. 3547). Excited by visible wavelengths (450 nm). Has no effect on firing of pyramidal neurons in mice; uncaging with blue light alters firing rate of COM and CPn neurons, which is blocked by MDL 100907 (Cat. No. 4173).
许可信息
Sold under licence from Columbia University
技术数据 for RuBi-5-HT
| 分子量 | 955.66 |
| 公式 | C33H37F12N6OP3Ru |
| 储存 | Store at -20°C |
| PubChem ID | 91826073 |
| InChI Key | CNCGWUINLFSMHP-UHFFFAOYSA-N |
| Smiles | [Ru++].CP(C)C.F[P-](F)(F)(F)(F)F.F[P-](F)(F)(F)(F)F.C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1.NCCC1=CNC2=C1C=C(O)C=C2 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
溶解性 for RuBi-5-HT
请参阅 RuBi-5-HT（目录编号 3856）溶解性指南。
产品说明书 for RuBi-5-HT
参考文献 for RuBi-5-HT
参考文献是支持产品生物活性的出版物。
Zayat et al (2006) Ruthenium(II) bipyridyl complexes as photolabile caging groups for amines. Inorg. Chem. 45 1728 PMID: 16471986
Cabrera et al (2017) A visible-light-sensitive caged serotonin. ACS Chem.Neurosci. 8 1036 PMID: 28460173
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关键词: RuBi-5-HT, RuBi-5-HT supplier, caged, serotonin, compounds, neurotransmitters, 5-HT, receptors, serotonergic, Non-selective, Caged, 5HT, Compounds, 3856, Tocris Bioscience
1 篇 RuBi-5-HT 的引用文献
引用文献是使用了 Tocris 产品的出版物。 RuBi-5-HT 的部分引用包括：
Baj et al (2012) Physical exercise and antidepressants enhance BDNF targeting in hippocampal CA3 dendrites: further evidence of a spatial code for BDNF splice variants. Neuropsychopharmacology 37 1600 PMID: 22318196
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该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
5-HT Receptors Scientific Review
Written by Nicholas M. Barnes and John F. Neumaier, this review summarizes the various serotonin receptor subtypes and their importance in mediating the role of serotonin in numerous physiological and pharmacological processes. Compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.