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Submit ReviewRuBi-Nicotine is a ruthenium-bisbipyridine-caged nicotine, excitable by irradiation with visible light. Undergoes rapid photolysis to release nicotine (< 20 ns); exhibits a high quantum yield. Induces action potential propagation in Retzius neurons of leech ganglia with no detectable toxicity at a concentration of 1 mM.
Sold under licence from Columbia University
分子量 | 808.81 |
公式 | C40H44Cl2N8Ru |
储存 | Store at -20°C |
CAS Number | 1256362-30-7 |
PubChem ID | 90488888 |
InChI Key | DRYNYXIOLIUZSG-ZPFSJBFKSA-L |
Smiles | [Cl-].[Cl-].[Ru++].C1=CN=C(C=C1)C1=CC=CC=N1.C1=CC=C(N=C1)C1=CC=CC=N1.[H][C@]1(CCCN1C)C1=CC=CN=C1.[H][C@]1(CCCN1C)C1=CC=CN=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Filevich et al (2010) A caged nicotine with nanosecond range kinetics and visible light sensitivity. J.Inorg.Biochem. 104 1248 PMID: 20825994
关键词: RuBi-Nicotine, RuBi-Nicotine supplier, RuBiNicotine, caged, compounds, nicotinics, cholinergics, acetylcholine, receptors, nAChRs, agonist, excitatory, Nicotinic, Receptors, (Non-selective), Caged, Compounds, 3855, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 RuBi-Nicotine 的部分引用包括:
Lorna W et al (2022) Axonal α7* nicotinic acetylcholine receptors modulate glutamatergic signaling and synaptic vesicle organization in ventral hippocampal projections. Front Neural Circuits 16 978837 PMID: 36213206
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