Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit ReviewRWJ 52353
Discontinued Product
3935 has been discontinued.
View all Adrenergic α<sub>2</sub> Receptors products.
说明： α2D agonist
化学名： 5-(6,7-Dihydrobenzo[b]thien-4-yl-1H-imidazole hydrochloride
纯度： ≥98% (HPLC)
生物活性 for RWJ 52353
RWJ 52353 is a agonist of the α2D adrenergic receptor (Ki values are 1.5, 254, 443 and 621 nM for α2D, α2A, α1 and α2B adrenergic receptors respectively).
技术数据 for RWJ 52353
| 分子量 | 202.28 |
| 公式 | C11H10N2S |
| 储存 | Store at +4°C |
| 纯度 | ≥98% (HPLC) |
| CAS Number | 245744-10-9 |
| PubChem ID | 71752148 |
| InChI Key | LIHWQUZNTRDJFW-UHFFFAOYSA-N |
| Smiles | C1(SC=C2)=C2C(C3=CN=CN3)=CCC1.Cl |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for RWJ 52353
参考文献 for RWJ 52353
参考文献是支持产品生物活性的出版物。
Ross et al (2000) α2 adrenoceptor agonists as potential analgesic agents. 2. Discovery of 4-(4-imidazo)-1,3-dimethyl-6,7-dihydrothianaphthene as a high-affinity ligand for the α2D adrenergic receptor. J.Med.Chem. 43 765 PMID: 10753480
Amphoux et al (2010) Inhibitory and facilitatory actions of isocyanine derivatives at human and rat organic cation transporters 1, 2 and 3: a comparison to human α1- and α2-adrenoceptor subtypes. Eur.J.Pharmacol. 634 1 PMID: 20170649
按产品操作查看相关产品
关键词: RWJ 52353, RWJ 52353 supplier, RWJ52353, agonists, alpha2D, a2d, α2d, adrenergic, receptors, adrenoceptors, Adrenergic, Alpha-2, Receptors, 3935, Tocris Bioscience
RWJ 52353 的评论
目前没有该产品的评论。 Be the first to review RWJ 52353 and earn rewards!
Have you used RWJ 52353?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.
Parkinson's Disease Poster
Parkinson's disease (PD) causes chronic disability and is the second most common neurodegenerative condition. This poster outlines the neurobiology of the disease, as well as highlighting current therapeutic treatments for symptomatic PD, and emerging therapeutic strategies to delay PD onset and progression.