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S 07662

Cat. No. 5188 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

5188 has been discontinued.

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说明： Constitutive androstane receptor (CAR) inverse agonist
化学名： N-[(2-Methyl-3-benzofuranyl)methyl]-N'-(2-thienylmethyl)urea
纯度： ≥98% (HPLC)
说明书
引用文献
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生物活性 技术数据 说明书 参考文献

生物活性 for S 07662

S 07662 is an inverse agonist of the constitutive androstane receptor (CAR). Inhibits CAR activity via recruitment of nuclear receptor co-repressor (NCoR). Suppresses CITCO-induced CYP2B6 gene expression in human primary hepatocytes.

技术数据 for S 07662

分子量 300.38
公式 C16H16N2O2S
储存 Store at +4°C
纯度 ≥98% (HPLC)
CAS Number 883226-64-0
PubChem ID 2732040
InChI Key UITFWLJMEZPXOF-UHFFFAOYSA-N
Smiles CC2=C(CNC(NCC3=CC=CS3)=O)C1=CC=CC=C1O2

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

参考文献 for S 07662

参考文献是支持产品生物活性的出版物。

Küblbeck et al (2011) New in vitro tools to study human constitutive androstane receptor (CAR) biology: discovery and comparison of human CAR inverse agonists. Mol.Pharm. 8 2424 PMID: 22044162

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关键词: S 07662, S 07662 supplier, S07662, inverse, agonists, constitutive, androstane, receptors, CAR, nuclear, Constitutive, Androstane, Receptor, 5188, Tocris Bioscience

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