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Submit Review(S)-Methylisothiourea sulfate is a highly selective, potent competitive inhibitor of iNOS.
分子量 | 278.36 |
公式 | C4H14N4O4S3 |
储存 | Store at RT |
CAS Number | 867-44-7 |
PubChem ID | 13347 |
InChI Key | BZZXQZOBAUXLHZ-UHFFFAOYSA-N |
Smiles | NC(SC)=[NH2+].NC(SC)=[NH2+].[O-]S([O-])(=O)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Iuvone et al (1997) Differential effect of L-NAME and S-methyl-isothiourea on leukocyte emigration in carrageenin-soaked sponge implants in rat. Br.J.Pharmacol. 121 1637 PMID: 9283697
Southan et al (1995) Isothioureas - potent inhibitors of nitric oxide synthases with variable isoform selectivity. Br.J.Pharmacol. 114 510 PMID: 7533622
关键词: (S)-Methylisothiourea sulfate, (S)-Methylisothiourea sulfate supplier, selective, iNOS, inhibitors, inhibits, Nitric, Oxide, Signaling, Signalling, Inducible, NO, Synthases, SMT, 0776, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 (S)-Methylisothiourea sulfate 的部分引用包括:
Chan et al (2007) Protein kinase C-dependent mitochondrial translocation of proapoptotic protein Bax on activation of inducible nitric-oxide synthase in rostral ventrolateral medulla mediates cardiovascular depression during experimental endotoxemia. Mol Pharmacol 71 1129 PMID: 17227955
Chang et al (2002) Differential contributions of nitric oxide synthase isoforms at hippocampal formation to negative feedback regulation of penile erection in the rat. Br J Pharmacol 136 43313 PMID: 11976262
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