Submit a Review & Earn an Amazon Gift Card
You can now submit reviews for your favorite Tocris products. Your review will help other researchers decide on the best products for their research. Why not submit a review today?!
Submit Review(S)-(-)-Pindolol
Discontinued Product
1060 has been discontinued.
View all Adrenergic β<sub>3</sub> Receptors products.
说明： β3 partial agonist; also 5-HT1A and 5-HT1B antagonist; more active enantiomer of pindolol (Cat. No. 0994)
化学名： (S)-1-(1H-indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol
纯度： ≥99% (HPLC)
生物活性 for (S)-(-)-Pindolol
(S)-(-)-Pindolol is a 5-HT1A/1B receptor antagonist, with roughly equal affinity for each subtype. A partial agonist at mouse and human β3-adrenoceptors. More active enantiomer of pindolol.
Racemate also available.
技术数据 for (S)-(-)-Pindolol
| 分子量 | 248.32 |
| 公式 | C14H20N2O2 |
| 储存 | Desiccate at +4°C |
| 纯度 | ≥99% (HPLC) |
| CAS Number | 26328-11-0 |
| PubChem ID | 688095 |
| InChI Key | JZQKKSLKJUAGIC-NSHDSACASA-N |
| Smiles | CC(C)NC[C@H](O)COC1=C2C=CNC2=CC=C1 |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for (S)-(-)-Pindolol
参考文献 for (S)-(-)-Pindolol
参考文献是支持产品生物活性的出版物。
Corradetti et al (1998) Antagonist properties of (-)-pindolol and WAY 100635 at somatodendritic and postsynaptic 5-HT1A receptors in the rat brain. Br.J.Pharmacol. 123 449 PMID: 9504386
Kalkman (1989) β-Adrenoceptor blockade in rats enhances the ambulation induced by 5-HT1A receptor agonists. Eur.J.Pharmacol. 173 121 PMID: 2576226
Walter et al (1984) Stimulant and blocking effects of optical isomers of pin. on the sinoatrial node and trachea of guinea pig. Role of β-adrenoceptor subtypes in the dissociation between blockade and stimulation. Naunyn Schmiedebergs Arch.Pharmacol. 327 159 PMID: 6092972
按标靶查看相关产品
按产品操作查看相关产品
关键词: (S)-(-)-Pindolol, (S)-(-)-Pindolol supplier, β3-adrenoceptor, b3-adrenoceptor, β3-adrenergic, b3-adrenergic, partial, agonists, Serotonin, 5-HT1A, Receptors, 5-HT1B, Adrenergic, Beta-3, 1060, Tocris Bioscience
1 篇 (S)-(-)-Pindolol 的引用文献
引用文献是使用了 Tocris 产品的出版物。 (S)-(-)-Pindolol 的部分引用包括：
Kaya et al (2009) Coupling of β2-adrenoceptors to XLαs and Gαs: a new insight into ligand-induced G protein activation. Front Neurosci 329 350 PMID: 19144685
(S)-(-)-Pindolol 的评论
目前没有该产品的评论。 Be the first to review (S)-(-)-Pindolol and earn rewards!
Have you used (S)-(-)-Pindolol?
Submit a review and receive an Amazon gift card.
$50/€35/£30/$50CAN/¥300 Yuan/¥5000 Yen for first to review with an image
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
该领域的文献
Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意，Tocris 仅会向正规科研企业/机构地址发送文献。
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.