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Sarafotoxin S6a

Cat. No. 1899 提交评论 说明书 / 分析证书（CoA） / 化学品安全技术说明书（SDS）

Discontinued Product

1899 has been discontinued.

View all Non-selective Endothelin products.
说明： Endothelin receptor agonist
说明书
引用文献
评论
生物活性 技术数据 说明书 参考文献

生物活性 for Sarafotoxin S6a

Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.

技术数据 for Sarafotoxin S6a

分子量 2514.85
公式 C105H156N28O34S5
序列 CSCKDMTDKECLNFCHQDVIW

(Modifications: Disulfide bridge between 1 - 15, 3 - 11)
储存 Desiccate at -20°C
CAS Number 126738-34-9
PubChem ID 71308664
InChI Key BOQKWORWRAYXSI-SQCNKGOOSA-N
Smiles [H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O

上方提供的技术数据仅供参考。批次相关数据请参见分析证书。

Tocris products are intended for laboratory research use only, unless stated otherwise.

产品说明书 for Sarafotoxin S6a

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化学品安全技术说明书

参考文献 for Sarafotoxin S6a

参考文献是支持产品生物活性的出版物。

Minkes et al (1992) Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic vascular beds. Am.J.Physiol. 262 H852 PMID: 1348398

Raffa et al (1996) Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. J.Pharmacol.Exp.Ther. 276 647 PMID: 8632332

Schoeffter and Randriantsoa (1993) Differences between endothelial receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur.J.Pharmacol. 249 199 PMID: 8287901

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关键词: Sarafotoxin S6a, Sarafotoxin S6a supplier, Endothelin, receptor, agonists, Non-Selective, ET, Receptors, SarafotoxinS6a, Non-selective, 1899, Tocris Bioscience

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