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Submit ReviewVasoconstrictor peptide; non-selective endothelin receptor agonist.
分子量 | 2564 |
公式 | C110H159N27O34S5 |
序列 |
CSCKDMTDKECLYFCHQDVIW (Modifications: Disulfide bridge between: 1-15, 3-11) |
储存 | Desiccate at -20°C |
CAS Number | 116303-65-2 |
PubChem ID | 71308726 |
InChI Key | ZHRYDGYRZIWZPS-RAALVGGVSA-N |
Smiles | [H]N[C@H]1CSSC[C@H](NC(=O)[C@H](CC2=CC=CC=C2)NC(=O)[C@H](CC2=CC=C(O)C=C2)NC(=O)[C@H](CC(C)C)NC(=O)[C@@H]2CSSC[C@H](NC(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCSC)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N2)C(=O)N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=CNC2=C1C=CC=C2)C(O)=O |
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Tocris products are intended for laboratory research use only, unless stated otherwise.
参考文献是支持产品生物活性的出版物。
Aimoto et al (1990) Studies on the disulfide bridges of sarafotoxins. Chemical synthesis of sarafotoxin S6B and its homologue with different disulfide bridges. Biochem.Int. 21 1051 PMID: 2080919
Bax et al (1994) Different endothelin receptors involved in endothelin-1- and sarafotoxin S6B-induced contractions of the human isolated coronary artery. Br.J.Pharmacol. 113 1471 PMID: 7889304
Devadason and Henry (1997) Comparison of the contractile effects and binding kinetics of endothelin-1 and sarafotoxin S6b in rat isolated renal artery. Br.J.Pharmacol. 121 253 PMID: 9154335
关键词: Sarafotoxin S6b, Sarafotoxin S6b supplier, Endothelin, receptor, agonists, non-selective, Non-Selective, ET, Receptors, ETA, ETB, SarafotoxinS6b, Non-selective, 1174, Tocris Bioscience
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