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说明： GlyT1 inhibitor
化学名： N-Methylglycine
生物活性 for Sarcosine
Sarcosine is an endogenous inhibitor of GlyT1 that displays antipsychotic activity. Potentiates the action of glycine on the NMDA glycine binding site.
技术数据 for Sarcosine
| 分子量 | 89.09 |
| 公式 | C3H7NO2 |
| 储存 | Store at RT |
| CAS Number | 107-97-1 |
| PubChem ID | 1088 |
| InChI Key | FSYKKLYZXJSNPZ-UHFFFAOYSA-N |
| Smiles | OC(CNC)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
Tocris products are intended for laboratory research use only, unless stated otherwise.
产品说明书 for Sarcosine
参考文献 for Sarcosine
参考文献是支持产品生物活性的出版物。
Tsai et al (2004) Glycine transporter I inhibitor, N-methylglycine (Sarcosine), added to antipsychotics for the treatment of schizophrenia. Biol.Psychiatry 55 452 PMID: 15023571
Singh and Singh (2011) Meta-analysis of the efficacy of adjunctive NMDA receptor modulators in chronic schizophrenia. CNS Drugs. 25 859 PMID: 21936588
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关键词: Sarcosine, Sarcosine supplier, GlyT1, inhibitors, inhibits, Glycine, Transporters, Monoamine, Neurotransmitter, 2975, Tocris Bioscience
1 篇 Sarcosine 的引用文献
引用文献是使用了 Tocris 产品的出版物。 Sarcosine 的部分引用包括：
Yoshikawa et al (2012) Glycine transporter type 2 (GlyT2) inhibitor ameliorates bladder overactivity and nociceptive behavior in rats. Eur Urol 62 704 PMID: 22341128
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