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Submit ReviewSecretin (human) is a gastrointestinal peptide that stimulates pancreatic and biliary secretion. Also thought to play a role in the regulation of the hypothalamus-pituitary-adrenal axis.
Secretin (rat) also available.
分子量 | 3039.44 |
公式 | C130H220N44O40 |
序列 |
HSDGTFTSELSRLREGARLQRLLQGLV (Modifications: Val-27 = C-terminal amide) |
储存 | Store at -20°C |
纯度 | ≥95% (HPLC) |
CAS Number | 108153-74-8 |
PubChem ID | 16158474 |
InChI Key | OWMZNFCDEHGFEP-NFBCVYDUSA-N |
Smiles | [H]N[C@@H](CC1=CNC=N1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(O)=O)C(=O)NCC(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(N)=O |
上方提供的技术数据仅供参考。批次相关数据请参见分析证书。
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溶解性 | Soluble to 1 mg/ml in water |
参考文献是支持产品生物活性的出版物。
Nussdorfer et al (2000) Secr., glucagon, gastric inhibitor polypeptide, parathyroid hormone, and related peptides in the regulation of the hypothalamus-pituitary-adrenal axis. Peptides 21 309 PMID: 10764961
Sherwood et al (2000) The origin and function of the pituitary adenylate cyclase-activating polypeptide (PACAP)/Glucagon superfamily. Endocr.Rev. 21 619 PMID: 11133067
If you know of a relevant reference for Secretin (human), please let us know.
关键词: Secretin (human), Secretin (human) supplier, Gastrointestinal, peptide, Secretin, Receptors, Glucagon, 1918, Tocris Bioscience
引用文献是使用了 Tocris 产品的出版物。 Secretin (human) 的部分引用包括:
Lee et al (2012) Secr. receptor promotes the proliferation of endocrine tumor cells via the PI3K/AKT pathway. Mol Endocrinol 26 1394 PMID: 22692904
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Tocris offers the following scientific literature in this area to showcase our products. We invite you to request* your copy today!
*请注意,Tocris 仅会向正规科研企业/机构地址发送文献。
Written by Sonia Tucci, Lynsay Kobelis and Tim Kirkham, this review provides a synopsis of the increasing number of peptides that have been implicated in appetite regulation and energy homeostasis; putative roles of the major peptides are outlined and compounds available from Tocris are listed.